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Peer reviewedOpen accessInfluenzaMeaslesRubellaTuberculosisVaricellaPertussis

Vaccine-Preventable Disease Outbreaks Among Healthcare Workers: A Scoping Review

Clinical Infectious Diseases·

Tasnim Hasan, Michelle Lynch, Catherine King, Charbel Wehbe, Martin Plymoth, Md Saiful Islam, Theodore Iannuzzi, Aiken Dao, Jana Lai, Alexandra Martiniuk, Shalini Desai, Meru Sheel

DOI
10.1093/cid/ciae209
PMID
38630638
PMCID
PMC11327795
OpenAlex
W4394868999
Study type
Journal article
Publisher
Oxford University Press (OUP)
Article type
journal-article
Integrity
current

Why this research matters now

Vaccine-preventable disease outbreaks among healthcare workers result in morbidity and mortality, disrupt healthcare services for patients and visitors, and impose additional burden on healthcare systems. The findings underscore the importance of vaccination among healthcare workers.

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Structured evidence summary

Research question

This scoping review aimed to characterize the epidemiology of vaccine-preventable disease outbreaks among healthcare workers, focusing on diseases covered by the ten vaccines recommended by the World Health Organization for this occupational group.

Study design

Scoping review of literature published from 2000 through April 2022, searching four databases (CINAHL, MEDLINE, Global Health, EMBASE) without language or study-type restrictions. Articles reporting vaccine-preventable disease outbreaks in healthcare workers were included.

Population and setting

Healthcare workers experiencing outbreaks in hospitals and long-term care facilities. Most identified studies originated from high- and upper-middle-income countries, with 93% of the 216 included articles from these settings.

Main findings

The search identified 216 articles from 9363 records, describing outbreaks of six vaccine-preventable diseases: influenza, measles, varicella, tuberculosis, pertussis, and rubella. Most outbreaks occurred in hospitals, though several influenza outbreaks were reported in long-term-care facilities. Vaccination rates among healthcare workers were rarely documented in the available data.

Public-health relevance

Vaccine-preventable disease outbreaks among healthcare workers result in morbidity and mortality, disrupt healthcare services for patients and visitors, and impose additional burden on healthcare systems. The findings underscore the importance of vaccination among healthcare workers.

Important limitations

This summary is limited to the supplied single-article abstract and metadata and requires the original paper for decision-grade interpretation. The abstract notes that vaccination rates were rarely reported in the outbreak data, limiting assessment of vaccine coverage as a contributing factor.

GIDS interpretation

This scoping review synthesizes outbreak reports across six vaccine-preventable diseases in healthcare settings and may support contextual understanding of disease transmission patterns in occupational health contexts. The classifier links indicate associations with measles, tuberculosis, pertussis, influenza, rubella, varicella, and topics including outbreak investigation and vaccination.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 13 auditable classifier relationships to diseases, places, topics, and study design.

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