Two autochthonous cases of Crimean-Congo haemorrhagic fever and the One Health response, Thessaly, Greece, 2025
Eurosurveillance·
- DOI
- 10.2807/1560-7917.es.2025.30.50.2500717
- PMID
- 41414932
- PMCID
- PMC12719936
- OpenAlex
- W4417524976
- Study type
- Journal article
- Publisher
- European Centre for Disease Control and Prevention (ECDC)
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The occurrence of autochthonous transmission in a previously non-endemic country highlights the need for enhanced surveillance, vigilance, and multisectoral collaboration for Crimean-Congo haemorrhagic fever, particularly in countries bordering endemic regions.
Structured evidence summary
Research question
This report describes the investigation and public health response to two autochthonous Crimean-Congo haemorrhagic fever cases in Thessaly, Greece, in June 2025.
Study design
Outbreak investigation and response report documenting case investigation, contact tracing, infection prevention and control measures, field investigation, vector and animal host interventions, and awareness-raising activities.
Population and setting
The cases occurred in Thessaly, Greece, involving a fatal index case and a healthcare worker who was secondarily infected. Greece had reported only one previous autochthonous case in 2008 and is considered non-endemic, though neighboring countries have endemic transmission.
Main findings
Two autochthonous Crimean-Congo haemorrhagic fever cases were identified in June 2025, including a fatal index case and a secondary infection in a healthcare worker. The event was characterized as unexpected given Greece's non-endemic status and triggered a multisectoral One Health response.
Public-health relevance
The occurrence of autochthonous transmission in a previously non-endemic country highlights the need for enhanced surveillance, vigilance, and multisectoral collaboration for Crimean-Congo haemorrhagic fever, particularly in countries bordering endemic regions.
Important limitations
This summary is limited to the supplied single-article abstract and bibliographic metadata. Full interpretation of study methods, completeness of the outbreak investigation, and detailed findings requires review of the original published article.
GIDS interpretation
This article would be discoverable through disease classifiers for hemorrhagic fever, geographic classifiers for Greece, and topic classifiers for One Health, outbreak investigation, and surveillance. The report provides context for understanding emergence of Crimean-Congo haemorrhagic fever in previously non-endemic settings.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 9 auditable classifier relationships to diseases, places, topics, and study design.