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Peer reviewedOpen accessMonkeypox

Stability of Monkeypox Virus in Body Fluids and Wastewater

Emerging Infectious Diseases·

Claude Kwe Yinda, Dylan H. Morris, Robert J. Fischer, Shane Gallogly, Zachary A. Weishampel, Julia R. Port, Trenton Bushmaker, Jonathan E. Schulz, Kyle Bibby, Neeltje van Doremalen, James O. Lloyd-Smith, Vincent J. Munster

DOI
10.3201/eid2910.230824
PMID
37735747
PMCID
PMC10521604
OpenAlex
W4386945244
Study type
Journal article
Publisher
Centers for Disease Control and Prevention (CDC)
Article type
journal-article
Integrity
current

Why this research matters now

Findings indicate that sufficient environmental MPXV stability could support transmission in healthcare settings, where exposure and dose-response are likely limiting factors.

01

Structured evidence summary

Research question

The study evaluates the environmental stability of monkeypox virus (MPXV) in body fluids and wastewater, and assesses decontamination effectiveness across different media and temperatures.

Study design

A laboratory-based experimental study examining MPXV decay across temperatures, suspending media, and surfaces, and testing decontamination methods including chlorination.

Population and setting

Laboratory experiments using MPXV suspended in various body fluids, solutions, surfaces, and wastewater; no human or clinical population is described.

Main findings

MPXV decay was faster at higher temperatures and varied by suspending medium. More proteinaceous fluids supported greater persistence. Chlorination was effective only at higher concentrations, and wastewater was harder to decontaminate than deionized water.

Public-health relevance

Findings indicate that sufficient environmental MPXV stability could support transmission in healthcare settings, where exposure and dose-response are likely limiting factors.

Important limitations

The abstract does not state explicit limitations. This summary is limited to the supplied single-article abstract and metadata, and the original paper is required for decision-grade interpretation.

GIDS interpretation

The article is classified under outbreak investigation, transmission dynamics, environment, and surveillance, which may aid its discoverability for users searching MPXV stability or environmental transmission evidence. This classification reflects metadata only and does not link the paper to any active surveillance signal.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 11 auditable classifier relationships to diseases, places, topics, and study design.

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