Global search

Find data and evidence

Type at least 2 characters. Use arrow keys to review and Enter to open.

Peer reviewedOpen accessCOVID-19Marburg virus diseaseEbola

Outbreak of Marburg Virus Disease, Equatorial Guinea, 2023

Emerging Infectious Diseases·

Stephanie Ngai, Egmond Samir Evers, Angela Katherine Lao Seoane, George Ameh, Julienne N. Anoko, Céline Barnadas, Mary J. Choi, Janet Diaz, Luca Fontana, Pierre Formenty, Ingrid Hammermeister Nezu, Frédérique Jacquerioz, John Klena, Henry Laurenson-Schafer, Olivier le Polain de Waroux, Anaïs Legand, Raquel Medialdea Carrera, Tatiana Metcalf, Joel Montgomery, Silvia Morreale, María E. Negrón, Justino Obama Nvé, Mitoha Ondo’o Ayekaba, Boris I. Pavlin, Trevor Shoemaker, Yaimara Torres Hernandez, Mabel Varona Venta, Emily Z. Gutierrez, Florentino Abaga Ondo Ndoho

DOI
10.3201/eid3105.241749
PMID
40180579
PMCID
PMC12044228
OpenAlex
W4409182814
Study type
Journal article
Publisher
Centers for Disease Control and Prevention (CDC)
Article type
journal-article
Integrity
current

Why this research matters now

The abstract emphasizes early isolation of symptomatic patients, community engagement, and stronger surveillance as priorities for outbreak control. It also notes that additional outbreak analysis and a One Health surveillance approach may support preparedness for possible future spillover events.

01

Structured evidence summary

Research question

The article addresses the 2023 Marburg virus disease outbreak in Equatorial Guinea, focusing on response organization, epidemiologic characteristics, transmission patterns, and timing measures such as serial interval and care-seeking or outcomes.

Study design

The abstract describes an outbreak investigation using laboratory-confirmed and probable case classifications, with descriptive epidemiologic analysis of cases, transmission chains, clinical features, risk factors, and timing intervals.

Population and setting

The reported setting was Equatorial Guinea during the February 2023 Marburg virus disease outbreak. The abstract identifies 39 total confirmed or probable cases across five districts, with transmission described in households and healthcare environments.

Main findings

The abstract reports 16 laboratory-confirmed and 23 probable cases, with a 90% case-fatality ratio. It also reports multiple transmission chains without clear links between them, clustering among families and healthcare settings, a median serial interval of 18.5 days, and transmission occurring mostly later in illness.

Public-health relevance

The abstract emphasizes early isolation of symptomatic patients, community engagement, and stronger surveillance as priorities for outbreak control. It also notes that additional outbreak analysis and a One Health surveillance approach may support preparedness for possible future spillover events.

Important limitations

The abstract does not provide detailed methods, ascertainment procedures, uncertainty intervals, or analytic limitations. This summary is limited to the supplied single-article abstract and metadata, and the full article would be needed for decision-grade interpretation.

GIDS interpretation

The supplied classifiers make the article discoverable under Marburg virus disease, Equatorial Guinea, outbreak investigation, and transmission dynamics. The additional disease labels should be treated as indexing context only and not as evidence of findings beyond the abstract.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 11 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseabout diseaseabout diseaseaddresses topicaddresses topichas pathogen typestudied instudied population settingstudies pathogenstudies pathogenuses study design