Transmission Pathways of Zoonotic Influenza Viruses and Influencing Factors: A Systematic Review of Recent Findings.
Viruses·
- DOI
- 10.3390/v17060857
- PMID
- 40573448
- PMCID
- PMC12197345
- OpenAlex
- W4411379836
- Study type
- Systematic review
- Publisher
- Publisher unavailable
- Article type
- journal-article
- Integrity
- current
Why this research matters now
Clarifying these transmission mechanisms supports improved pandemic preparedness and underscores the importance of coordinated, multi-sectoral health frameworks to mitigate future spillover threats.
Structured evidence summary
Research question
This systematic review synthesizes recent literature to identify how zoonotic influenza viruses move between animal populations and spill over into human communities, alongside the variables that facilitate these cross-species transfers.
Study design
The authors conducted a systematic review adhering to PRISMA standards, screening thousands of database records to select relevant publications spanning seven years.
Population and setting
The analysis encompasses studies involving wild and domestic animal reservoirs, as well as human populations affected by cross-species viral transfer, without restricting geographic boundaries.
Main findings
The synthesis highlights existing knowledge on host, environmental, and viral drivers of transmission while revealing substantial unexplored areas regarding interspecies movement, ecological influences, and regional zoonotic risks.
Public-health relevance
Clarifying these transmission mechanisms supports improved pandemic preparedness and underscores the importance of coordinated, multi-sectoral health frameworks to mitigate future spillover threats.
Important limitations
The authors acknowledge that the reviewed corpus contains notable gaps, specifically regarding viral circulation across varied animal hosts, the precise influence of ecological variables, and regional variations in cross-species risk.
GIDS interpretation
This work situates ongoing academic inquiry into viral ecology within established international research priorities, offering a consolidated reference point for scholars tracking cross-species pathogen movement.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 8 auditable classifier relationships to diseases, places, topics, and study design.