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Peer reviewedOpen accessTyphoid fever

Efektivitas Penggunaan Obat Antibiotik pada Pasien Demam <i>Typhoid</i>

Pharmaceutical Journal·

Masyithoh Nur Wafiqoh, Kathina Deswiaqsa, Nugra Irianta Denashurya

DOI
10.67865/wp6f3871
PMID
PMCID
OpenAlex
W7202261628
Study type
Journal article
Publisher
Sekolah Tinggi Ilmu Kesehatan Sambas
Article type
journal-article
Integrity
current

Why this research matters now

Assessing these treatment metrics addresses documented concerns regarding therapeutic failure, mortality risks, and potential antimicrobial resistance development.

01

Structured evidence summary

Research question

The investigation seeks to evaluate how effectively administered antibiotics influence clinical recovery for individuals diagnosed with typhoid fever.

Study design

Researchers utilized a retrospective, non-experimental observational framework analyzed via paired sample t-tests.

Population and setting

The analytical cohort comprised 104 typhoid patients selected through purposive sampling from an initial registry of 140 cases.

Main findings

Ceftriaxone served as the primary prescription, correlating with statistically significant reductions in patient temperature and abbreviated hospitalization durations.

Public-health relevance

Assessing these treatment metrics addresses documented concerns regarding therapeutic failure, mortality risks, and potential antimicrobial resistance development.

Important limitations

The retrospective methodology and reliance on a small, non-randomized sample inherently restrict statistical power and broader generalizability.

GIDS interpretation

This publication supplies localized clinical performance data that researchers can reference when investigating typhoid management strategies or antimicrobial usage literature.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 7 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicaddresses topicevaluates interventionstudied population settinguses study design