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疾病概览

病毒性

人感染H7N9禽流感

H7N9

有证据支持的资料英文 6/7 个适用章节 · 中文 6/7 个适用章节更新于 2026年9月3日

H7N9是甲型流感病毒亚型,主要引起禽类流感,并可在接触感染禽类的人群中造成人感染[1]。该病毒自2013年起在中国报告人类感染[1],并与H5/H7亚型共同造成全球人类病例和死亡负担[2]。因其可跨物种传播并导致散发人感染,H7N9被视为具有大流行关注度的流感病毒之一[3]

阅读完整临床与流行病学资料7
定义

H7N9属于甲型流感病毒的一个亚型,主要在家禽和野鸟中流行[1]。它属于可从禽类动物源向哺乳动物溢出的人兽共患流感病毒谱系[4]。其家禽致病性分为低致病性与高致病性,但该分类依据鸡群严重程度,不能直接预测人类病例严重程度[1]

临床特征

人类感染H7N9后的症状可轻可重,可包括发热、腹泻和咳嗽,并可出现重症或死亡[1]。低致病性H7N9在家禽中可表现为轻微症状或无症状[1]。高致病性H7N9在家禽中可造成严重呼吸困难、产蛋量下降和突然死亡,但这些禽类表现不能直接等同于人类病情[1]

流行病学

H5和H7亚型禽流感病毒已造成全球2634例人类病例和1000余例死亡[2]。这些病毒已在野生鸟类和家禽中引发大量疫情,并造成自2005年以来至少4.22亿只家禽损失[2]。H7N9作为2013年出现并在中国广泛流行的H7亚型病毒,其人类感染具有散发性,并被视为具有大流行关注度的禽流感病毒之一[2][3]。中国采用扑杀与免疫相结合的策略,并接近清除了2013年出现的广泛流行H7N9病毒[2]

传播/暴露

H7N9可在家禽群和野鸟之间快速传播[1]。病毒可经感染禽类的唾液、黏液和粪便排出[1]。人类感染通常可追溯到与感染禽类或受污染材料的密切接触[1]。野生水鸟可能持续携带病毒,并可在迁徙中将其长距离移动[1]

高风险人群

人类感染H7N9通常见于接触感染禽类或受污染材料的人群[1]。在哺乳动物中,包括人类,A/H7N9感染较少见,病例多可追溯到与感染家禽或受污染材料的密切接触[1]

预防

针对H7N9禽流感的防控策略主要依托于病毒致病性分级与疫苗应急储备机制。基于该病毒对家禽养殖业的经济冲击,防控体系将其划分为高致病性与低致病性类别,判定依据主要为人工感染后鸡群的致死率阈值及血凝素蛋白结构特征,以此作为实施强化管控措施的基准[1]。在免疫预防层面,病毒持续的抗原漂移与变异增加了常规疫苗研发的难度,重大疫情爆发时往往需针对新发毒株快速调整疫苗组分[1]。目前相关人用疫苗已完成小规模临床测试,并确立了在疫情触发条件下向制药企业紧急调配候选疫苗病毒的标准化流程[1]

参考文献
  1. 1Wikipedia contributors. Influenza A virus subtype H7N9 - Wikipedia [Internet]. Wikipedia. cited 3 Sept 2026.Available from: https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H7N9
  2. 2Cargnin Faccin F et al. Pandemic preparedness through vaccine development for avian influenza viruses. Hum Vaccin Immunother. 2024 Dec 31. PMID: 38807261. doi: 10.1080/21645515.2024.2347019.PubMed: https://pubmed.ncbi.nlm.nih.gov/38807261/
  3. 3Webster RG et al. Continuing challenges in influenza. Ann N Y Acad Sci. 2014 Sep. PMID: 24891213. doi: 10.1111/nyas.12462.PubMed: https://pubmed.ncbi.nlm.nih.gov/24891213/
  4. 4Shi J et al. Alarming situation of emerging H5 and H7 avian influenza and effective control strategies. Emerg Microbes Infect. 2023 Dec. PMID: 36458831. doi: 10.1080/22221751.2022.2155072.PubMed: https://pubmed.ncbi.nlm.nih.gov/36458831/
编码登记
ICD-10
J09
ICD-11
1E30.0
核心统计
累计病例
1K
累计死亡
565
峰值月份
2017-01
覆盖区间
2 个报告国家 · 2013-05-10 → 2026-08-30

数据覆盖

报告国家和地区

2 个国家/地区

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文献链接仅用于发现研究,不会改变或验证上方的监测序列。

数据获取

本页面数据索引,含来源链接和更新信息。

行数1,458
更新2026-09-01
范围
分块4
来源1 序列 · 311 观测
官方数据来源机构、频率与说明26
China

China CDC Weekly

China

来源
MONTHLY网页

Monthly notifiable infectious disease reports published by China CDC.

China

National Disease Control and Prevention Administration

China

来源
MONTHLY网页

Official China public health bulletin and query portal.

China

PubMed

China

来源
MONTHLY网页

Biomedical literature discovery feed used as supplementary context.

Anhui, China

Public Health Science Data Center

Anhui, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Anhui, China

Provincial statutory infectious disease monthly report

Anhui, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Chongqing, China

Public Health Science Data Center

Chongqing, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Chongqing, China

Provincial statutory infectious disease monthly report

Chongqing, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Guangdong, China

Public Health Science Data Center

Guangdong, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Guangdong, China

Provincial statutory infectious disease monthly report

Guangdong, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Gansu, China

Public Health Science Data Center

Gansu, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Gansu, China

Provincial statutory infectious disease monthly report

Gansu, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Henan, China

Public Health Science Data Center

Henan, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Henan, China

Provincial statutory infectious disease monthly report

Henan, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Jiangsu, China

Public Health Science Data Center

Jiangsu, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Jiangsu, China

Provincial statutory infectious disease monthly report

Jiangsu, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Sichuan, China

Public Health Science Data Center

Sichuan, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Sichuan, China

Provincial statutory infectious disease monthly report

Sichuan, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Shandong, China

Public Health Science Data Center

Shandong, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Shandong, China

Provincial statutory infectious disease monthly report

Shandong, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Shanghai, China

Public Health Science Data Center

Shanghai, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Shanghai, China

Provincial statutory infectious disease monthly report

Shanghai, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Xinjiang, China

Public Health Science Data Center

Xinjiang, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Xinjiang, China

Provincial statutory infectious disease monthly report

Xinjiang, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Zhejiang, China

Public Health Science Data Center

Zhejiang, China

来源
每年official_datacenter_spreadsheet

Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.

Zhejiang, China

Provincial statutory infectious disease monthly report

Zhejiang, China

来源
每月official_provincial_report

Province-level statutory infectious disease report published by the responsible health authority.

Japan

日本 NIID/JIHS 周报

Japan

来源
每周网页

日本 NIID/JIHS 周度传染病监测数据。

分块公开数据

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