汉坦病毒是属于汉坦病毒科(Hantaviridae)的一组单链RNA病毒,由啮齿动物携带,可导致人类患严重的发热性疾病,包括汉坦病毒肺综合征(HPS)和肾综合征出血热(HFRS)[2][4]。
疾病概览
汉坦病毒感染
Hantavirus infection
汉坦病毒是一类由啮齿动物携带的单链RNA病毒,可引起人类严重疾病。每种汉坦病毒通常与特定的啮齿动物宿主相关,在宿主体内造成长期感染而不出现明显病症。该病毒与人类两种主要疾病相关:汉坦病毒肺综合征(HPS),主要在美洲报告;以及肾综合征出血热(HFRS),主要在欧洲和亚洲报告[1][2]。全球每年估计有10,000至超过100,000例感染,亚洲和欧洲负担最大,死亡率可达40%[2][3]。目前尚无获批的特效抗病毒治疗或疫苗,以支持性治疗为主,重点是密切临床监测以及呼吸、心脏和肾脏并发症的管理[1]。
阅读完整临床与流行病学资料6
早期症状与其他发热或呼吸道疾病相似,如流感、COVID-19、病毒性肺炎、钩端螺旋体病、登革热或败血症,诊断具有挑战性,因此仔细询问患者病史至关重要[1]。症状通常在接触后1至8周出现,包括发热、头痛、肌肉酸痛以及腹痛、恶心或呕吐等胃肠道症状[2]。汉坦病毒肺综合征可能迅速进展为咳嗽、呼吸急促、肺部积液和休克;肾综合征出血热后期可能出现低血压、出血性疾病和肾功能衰竭[2]。
全球每年估计有10,000至超过100,000例汉坦病毒感染,亚洲和欧洲的疾病负担最大[2]。汉坦病毒肺综合征主要在美洲报告,肾综合征出血热主要在欧洲和亚洲报告[2]。感染后死亡率可高达40%,具体取决于病毒类型和地理位置[3]。
人类通常通过接触受感染啮齿动物或其尿液、粪便或唾液而感染[2]。迄今为止,仅限于安第斯病毒在美洲部分地区存在有限的人传人传播证据[2]。在适当的感染预防和控制措施下,医疗保健相关传播风险非常低[1]。
预防汉坦病毒感染主要依赖于减少人与啮齿动物的接触,包括环境管理、食物储存防护以及家庭和工作场所的密封防鼠措施[1]。在暴发期间或怀疑病例时,早期识别和隔离病例、监测密切接触者以及采取标准感染预防措施对限制进一步传播至关重要[1]。在医疗环境中,应对所有患者实施标准预防措施,包括手卫生、环境清洁和安全处理血液及体液;对于疑似或确诊汉坦病毒感染,在护理过程中结合使用标准预防和基于传播途径的预防措施[1]。目前尚无获批的疫苗或特效治疗方法,但诱导中和抗体反应的免疫策略对开发预防措施具有重要意义[3]。
- 1World Health Organization. Hantavirus [Internet]. cited 3 Sept 2026.Available from: https://www.who.int/health-topics/hantavirus
- 2Afzal S et al. Hantavirus: an overview and advancements in therapeutic approaches for infection. Front Microbiol. 2023. PMID: 37901807. doi: 10.3389/fmicb.2023.1233433.PubMed: https://pubmed.ncbi.nlm.nih.gov/37901807/
- 3World Health Organization. Hantavirus [Internet]. cited 3 Sept 2026.Available from: https://www.who.int/news-room/fact-sheets/detail/hantavirus
- 4Engdahl TB et al. Humoral Immunity to Hantavirus Infection. mSphere. 2020 Jul 15. PMID: 32669473. doi: 10.1128/mSphere.00482-20.PubMed: https://pubmed.ncbi.nlm.nih.gov/32669473/
数据覆盖
报告国家和地区
各报告国家的趋势
月度变化趋势
研究雷达
近期相关研究
When rare zoonoses travel: Andes virus, hantavirus cardiopulmonary syndrome, and the preparedness gap
International Journal of Infectious Diseases
Outbreak of Hantavirus Pulmonary Syndrome, Los Santos, Panama, 1999–2000
Emerging Infectious Diseases
文献链接仅用于发现研究,不会改变或验证上方的监测序列。
数据获取
本页面数据索引,含来源链接和更新信息。
官方数据来源机构、频率与说明40
Austria AGES Radar for Infectious Diseases
Austria
AGES Radar monthly national source. Internal ingestion retains native categories; public release is disabled pending licence review.
ECDC Surveillance Atlas — Belgium Annual Baseline
Belgium
Belgium annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Bulgaria Annual Baseline
Bulgaria
Bulgaria annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Brazil DATASUS SINAN
Brazil
Brazil Ministry of Health DATASUS/SINAN public DBC microdata aggregated to national monthly notification counts.
Canada PHAC CNDSS Annual
Canada
Canada is the national jurisdiction; subdivision feeds are registered separately.
Switzerland FOPH IDD
Switzerland
Switzerland FOPH/BAG IDD mandatory reporting API normalized to national case rows. Monthly series may use the dashboard CHFL aggregate where CH-only monthly series are not exposed.
ECDC Surveillance Atlas — Cyprus Annual Baseline
Cyprus
Cyprus annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Czechia Annual Baseline
Czechia
Czechia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Germany RKI SurvStat 2.0
Germany
RKI SurvStat national weekly notification export; raw ZIP exports are retained and recent weeks are overwritten for revisions.
ECDC Surveillance Atlas — Estonia Annual Baseline
Estonia
Estonia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Spain Annual Baseline
Spain
Spain annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Finland THL Infectious Diseases Register
Finland
Finland THL Infectious Diseases Register national monthly case counts. The current month is ingested as provisional and the latest three months are refreshed for source revisions.
ECDC Surveillance Atlas — France Annual Baseline
France
France annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — United Kingdom Annual Baseline
United Kingdom
United Kingdom annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Greece Annual Baseline
Greece
Greece annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Hong Kong, China CHP Notifiable Diseases
Hong Kong, China
Hong Kong, China CHP annual notifiable infectious disease CSVs normalized to national monthly totals
ECDC Surveillance Atlas — Croatia Annual Baseline
Croatia
Croatia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Hungary Annual Baseline
Hungary
Hungary annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Ireland HPSC Notifiable Diseases Hub
Ireland
Ireland HPSC national weekly notifiable-disease totals from the official ArcGIS FeatureServer. Internal ingestion is enabled; public release remains disabled pending written redistribution permission.
冰岛卫生署年度传染病看板
Iceland
冰岛全国分病种年度病例通报;历史值可能追溯修订,并保持年度总量口径。
冰岛卫生署性病监测看板
Iceland
实验室与登记监测的月度性病诊断事实;官方看板按季度发布。
冰岛卫生署呼吸道感染周度看板
Iceland
按 ISO 周记录的呼吸道疾病诊断数;住院、样本和疫苗指标不计入诊断数。
冰岛卫生署历史传染病登记
Iceland
1997—2021 年官方历史登记表,年度与月度事实按原始粒度保留。
冰岛卫生署历史 ICD 临床月报
Iceland
Saga 电子病历 ICD 就诊数;与登记通报不可比并保持独立。
ECDC Surveillance Atlas — Italy Annual Baseline
Italy
Italy annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Liechtenstein Annual Baseline
Liechtenstein
Liechtenstein annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Lithuania Annual Baseline
Lithuania
Lithuania annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Luxembourg Annual Baseline
Luxembourg
Luxembourg annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Latvia Annual Baseline
Latvia
Latvia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Malta Annual Baseline
Malta
Malta annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Netherlands Annual Baseline
Netherlands
Netherlands annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Norway FHI MSIS Statistics Bank
Norway
Norway FHI MSIS national monthly notifications from the official Allvis frontend API; adapter contract checks guard the unversioned endpoint.
ECDC Surveillance Atlas — Poland Annual Baseline
Poland
Poland annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Portugal Annual Baseline
Portugal
Portugal annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Romania Annual Baseline
Romania
Romania annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Sweden Public Health Agency SmiNet
Sweden
Sweden SmiNet national monthly reported cases from the official Public Health Agency statistics pages; public release is enabled with closed-month publication and revisable recent-month refreshes.
ECDC Surveillance Atlas — Slovenia Annual Baseline
Slovenia
Slovenia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Slovakia Annual Baseline
Slovakia
Slovakia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
US CDC NNDSS
United States
CDC National Notifiable Diseases Surveillance System provisional data.
US CDC NHSS HIV
United States
CDC NNDSS weekly data plus NHSS annual national HIV diagnoses