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Peer reviewedOpen accessPlasmodium vivax malariaMalaria

Delayed diagnosis of Plasmodium vivax malaria and associated factors among Thai patients and patients from neighboring countries at the Hospital for Tropical Diseases, Bangkok, Thailand

Infection·

Sakarn Charoensakulchai, Noppadon Tangpukdee, Polrat Wilairatana, Srivicha Krudsood, Wiwat Chancharoenthana, Sant Muangnoicharoen, Panita Looareesuwan

DOI
10.1007/s15010-026-02930-8
PMID
42606671
PMCID
OpenAlex
W7203627798
Study type
Journal article
Publisher
Springer Science and Business Media LLC
Article type
journal-article
Integrity
current

Why this research matters now

Recognizing these temporal barriers supports the development of region-specific awareness campaigns and triage guidelines for fever management in areas experiencing reduced transmission.

01

Structured evidence summary

Research question

Investigates the frequency and contributing variables behind postponed clinical confirmation of Plasmodium vivax infections at a specialized urban hospital in Thailand.

Study design

A retrospective chart review analyzing fourteen years of admission records, employing multivariable modeling to contrast demographic and clinical profiles across diagnostic timeline groups.

Population and setting

Individuals presenting with confirmed parasitic infection at a Bangkok tropical disease facility, encompassing local residents and travelers from adjacent regions.

Main findings

Postponement exceeding four days occurred in nearly sixty percent of cases, driven primarily by patient hesitation rather than clinical assessment delays. Middle-aged adults, individuals in administrative roles, those without previous infection history, and patients initially receiving incorrect clinical evaluations demonstrated significantly elevated odds of postponement.

Public-health relevance

Recognizing these temporal barriers supports the development of region-specific awareness campaigns and triage guidelines for fever management in areas experiencing reduced transmission.

Important limitations

Relying on historical institutional records restricts real-time validation and may omit undocumented pre-admission interactions. Conducting the analysis at one tertiary facility constrains broader applicability to diverse healthcare systems.

GIDS interpretation

The manuscript supplies descriptive metrics regarding diagnostic timelines for a specific pathogen within a transitioning epidemiological landscape, establishing baseline context for regional health monitoring frameworks.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 8 auditable classifier relationships to diseases, places, topics, and study design.

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