Measles outbreak in Burkina Faso, 2009: A case–control study to determine risk factors and estimate vaccine effectiveness
Vaccine·
- DOI
- 10.1016/j.vaccine.2012.05.024
- PMID
- 22652399
- PMCID
- PMC6743076
- OpenAlex
- W2026625111
- Study type
- Case-control study
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The authors emphasize that findings support improved strategies to reduce missed vaccination opportunities and achieve high nationwide measles vaccination coverage to prevent large outbreaks and advance measles mortality reduction.
Structured evidence summary
Research question
The study aimed to describe a 2009 measles outbreak in Burkina Faso, identify risk factors for measles, and estimate measles vaccine effectiveness.
Study design
The investigation combined review of national surveillance and measles vaccine coverage data with a case-control study conducted in three geographic areas, using conditional logistic regression for risk factor analysis.
Population and setting
The study was set in three geographic areas of Burkina Faso and included case-patients and matched controls in two age strata (1–14 years and 15–30 years); controls were matched by age stratum and community.
Main findings
Lack of measles vaccination was the main risk factor for measles across all three geographic areas in both age strata. Among children aged 1–14 years, vaccine effectiveness of prior measles vaccination ranged from 84% to 94% across the three areas. Reported reasons for non-vaccination included limited knowledge of vaccination campaigns or of the need for measles vaccination, and absence during outreach or campaign activities.
Public-health relevance
The authors emphasize that findings support improved strategies to reduce missed vaccination opportunities and achieve high nationwide measles vaccination coverage to prevent large outbreaks and advance measles mortality reduction.
Important limitations
The abstract does not state explicit limitations of the study. This summary is limited to the supplied single-article abstract and metadata and should be supplemented with the original paper for decision-grade interpretation.
GIDS interpretation
The article is catalogued under measles, vaccination, outbreak investigation, vaccine effectiveness, and surveillance, which may aid discoverability of historical outbreak and vaccine-effectiveness evidence; the summary does not connect the paper to any live surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 14 auditable classifier relationships to diseases, places, topics, and study design.