Mumps Complications and Effects of Mumps Vaccination, England and Wales, 2002–2006
Emerging Infectious Diseases·
- DOI
- 10.3201/eid1704.101461
- PMID
- 21470456
- PMCID
- PMC3377415
- OpenAlex
- W2060424504
- Study type
- Journal article
- Publisher
- Centers for Disease Control and Prevention (CDC)
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The paper is relevant to understanding mumps outbreak burden and the complications that contributed to severe illness. It also frames vaccination as part of assessing mumps control strategies.
Structured evidence summary
Research question
The article examines how mumps complications varied during the 2004-2005 outbreak in England and Wales, and whether prior mumps vaccination was associated with different outcomes.
Study design
This is a journal article reporting an observational analysis of hospital admissions alongside enhanced mumps surveillance data. It compares outbreak and nonoutbreak periods and evaluates vaccination status against several outcomes.
Population and setting
The setting is England and Wales, focused on the largest mumps outbreak in 2004-2005. The data source appears to be mumps patients captured through surveillance and hospital records.
Main findings
The abstract reports more hospitalized cases with orchitis, meningitis, and pancreatitis during the outbreak than in nonoutbreak periods. It also reports lower odds of hospitalization, orchitis, and meningitis among people who had received one dose of MMR vaccine.
Public-health relevance
The paper is relevant to understanding mumps outbreak burden and the complications that contributed to severe illness. It also frames vaccination as part of assessing mumps control strategies.
Important limitations
The abstract does not state explicit study limitations. This summary is limited to the supplied single-article abstract and metadata, so the original paper is needed for decision-grade interpretation.
GIDS interpretation
This article is discoverable as outbreak-investigation and surveillance literature on mumps, with a vaccination component. The supplied materials do not support treating it as a live surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 14 auditable classifier relationships to diseases, places, topics, and study design.