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Peer reviewedOpen accessDiphtheria

Diphtheria outbreak, Northern Territory of Australia, 2025 to 2026

Eurosurveillance·

Anthony DK Draper, Mark Sistrom, Kimberley McMahon, Robert Duguid, Jerry Chen, Georgia Cramp, Thomas Cherian, Mirsaed Miri Nargesi, Dzulfikaar Sutandar, Kevin Freeman, Kelly Lomas, Tarrant Tolotta, Jenine C Gunn, Rowena Boyd, Jann Hennessy, Tinus Creeper, Jaimee Harbidge, Fatima Sarmiento, Rebecca Curr, Jennifer Yan, Joshua R Francis, Robert Baird, Hayley Stratton, Jane Davies, Catherine S Marshall, Sonja Janson, Nerida Moore, Rebecca Wardell, Eugene Athan, George Drewett, Liz Moore, Elly Layton, Unni Susil Kumar, Rosalind Webby, Ashish Yadav, Vicki L Krause, Bhavi Ravindran, Ella M Meumann

DOI
10.2807/1560-7917.es.2026.31.23.2600443
PMID
42283111
PMCID
PMC13263650
OpenAlex
Study type
Genomic study
Publisher
European Centre for Disease Control and Prevention (ECDC)
Article type
journal-article
Integrity
current

Why this research matters now

The event demonstrates that sustained immunization programs can be circumvented by specific socioeconomic and environmental risk factors, necessitating targeted monitoring of cutaneous manifestations.

01

Structured evidence summary

Research question

What epidemiological and clinical features characterize the recent diphtheria resurgence in the Northern Territory of Australia?

Study design

The authors conducted an outbreak investigation incorporating genomic epidemiology to document case distribution and transmission pathways.

Population and setting

Cases were identified across the Northern Territory of Australia, with spread concentrated in environments marked by high occupancy and suboptimal dermatological care.

Main findings

The cumulative count reached one hundred thirty-one infections, split between ninety-seven cutaneous and thirty-four respiratory presentations. Spread corresponded to overcrowded settings and deteriorated skin conditions, whereas prior immunization generally restricted illness severity.

Public-health relevance

The event demonstrates that sustained immunization programs can be circumvented by specific socioeconomic and environmental risk factors, necessitating targeted monitoring of cutaneous manifestations.

Important limitations

As an active outbreak report, the dataset may experience reporting delays and lacks comprehensive demographic breakdowns or extended clinical follow-up.

GIDS interpretation

This peer-reviewed article establishes a baseline reference for a previously absent pathogen strain, aiding future literature searches and contextual tracking of bacterial re-emergence events.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 11 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicaddresses topicaddresses topicevaluates interventionstudied instudied population settingstudies populationstudies populationuses study design