Hemoadsorption Therapy for Expanded Dengue Syndrome Patients : A Case Series Study
Journal of Chittagong Medical College Teachers' Association·
- DOI
- 10.3329/jcmcta.v37i1.91645
- PMID
- —
- PMCID
- —
- OpenAlex
- —
- Study type
- Guideline
- Publisher
- Bangladesh Academy of Sciences
- Article type
- journal-article
- Integrity
- current
Why this research matters now
Expanded dengue syndrome represents a rare but severe manifestation of dengue infection with multi-organ involvement and high fatality risk. The case series suggests hemoadsorption may offer a treatment option when standard intensive care fails, though the evidence base is limited to three cases.
Structured evidence summary
Research question
The case series examines whether hemoadsorption therapy can serve as an effective adjunct treatment for patients with expanded dengue syndrome who present with multi-organ involvement and do not improve with standard intensive care interventions.
Study design
This is a case series of three patients with expanded dengue syndrome treated in an intensive care unit. Hemoadsorption therapy was introduced after standard interventions failed to improve patient condition.
Population and setting
Three patients with expanded dengue syndrome involving multiple organs were treated in an intensive care unit setting. All patients received standard dengue management according to national guidelines before hemoadsorption was applied.
Main findings
All three patients with expanded dengue syndrome who underwent hemoadsorption therapy achieved full recovery without residual disability. The patients were discharged on the 8th, 10th, and 12th days of hospital stay respectively.
Public-health relevance
Expanded dengue syndrome represents a rare but severe manifestation of dengue infection with multi-organ involvement and high fatality risk. The case series suggests hemoadsorption may offer a treatment option when standard intensive care fails, though the evidence base is limited to three cases.
Important limitations
This summary relies solely on the supplied abstract and metadata. The case series design with only three patients provides limited evidence for establishing treatment efficacy or generalizability. The original paper is required for decision-grade interpretation including detailed patient selection criteria, hemoadsorption protocols, comparative outcomes, and potential confounding factors.
GIDS interpretation
The article was classified under dengue disease and treatment topics, reflecting its focus on a novel therapeutic approach for severe dengue complications. As a guideline-type study in a peer-reviewed journal, it may inform clinical decision-making for managing expanded dengue syndrome, though the small case series limits strength of evidence.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 8 auditable classifier relationships to diseases, places, topics, and study design.