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Peer reviewedOpen accessDengueMalaria

Severe Dengue and Dengue–Malaria Coinfection: A Case Series from a Referral Hospital in Montería, Colombia

Clinics and Practice·

Paula A. Avilés-Vergara, Dina Ricardo-Caldera, Osnamir Elias Bru-Cordero, Juan Alberto Miranda, Angie Paola Martínez Villera, Kevin Alexander Angulo Álvarez, María Carolina Geney Caro

DOI
10.3390/clinpract16080150
PMID
PMCID
OpenAlex
W7203627924
Study type
Journal article
Publisher
MDPI AG
Article type
journal-article
Integrity
current

Why this research matters now

Concurrent illness presentation complicates clinical assessment in tropical zones, suggesting that healthcare systems require enhanced diagnostic triage and continuous patient observation strategies.

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Structured evidence summary

Research question

The investigation aims to characterize the demographic and clinical profiles of individuals diagnosed with severe dengue, dengue accompanied by warning signs, or concurrent malaria infection.

Study design

Researchers conducted a retrospective chart review of hospitalized patients over a five-year period at a single tertiary facility.

Population and setting

The analyzed group comprised fifty-three adults and children presenting with varying dengue severity levels or dual parasitic infection at a Colombian referral center.

Main findings

Female patients experienced severe disease more frequently, while males predominated in warning sign and coinfection categories. Clinical indicators such as fluid leakage and elevated blood concentration were prominent in severe cases, and coinfection accounted for the majority of recorded fatalities.

Public-health relevance

Concurrent illness presentation complicates clinical assessment in tropical zones, suggesting that healthcare systems require enhanced diagnostic triage and continuous patient observation strategies.

Important limitations

The reliance on historical medical records from one location restricts broader applicability and may reflect local documentation practices rather than universal disease patterns.

GIDS interpretation

This article offers descriptive epidemiological data that may serve as a reference point for literature mapping or historical trend analysis within diagnostic and therapeutic research domains.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 11 auditable classifier relationships to diseases, places, topics, and study design.

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