Geographic evidence hub

Gambia research

Published infectious-disease research classified with a high-confidence geographic relationship to Gambia.

Published evidence: 3
Diseases: 6
Countries: 12
Topics: 8

Evidence stream

Published literature

3 publications

Peer reviewedOpen accessInvasive pneumococcal diseaseGenomic epidemiology Antimicrobial resistance Surveillance

DOI 10.1016/s1473-3099(19)30297-x ↗

Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study

Stephanie W Lo, Rebecca A Gladstone, Andries J van Tonder +86 more

The Lancet Infectious DiseasesJul 1, 2019

Open article ↗Invasive pneumococcal disease surveillance →

Type: Genomic study
Scope: Hong Kong, China, Israel, Gambia

Why it matters nowFindings suggest emerging non-vaccine serotypes may be shaped by local antibiotic-selective pressures, highlighting the need for continued genomic surveillance to inform future vaccine design.

Peer reviewedOpen accessGastroenteritisTreatment Vaccination Surveillance

DOI 10.1093/cid/cis761 ↗

The Global Enteric Multicenter Study (GEMS): Impetus, Rationale, and Genesis

M. M. Levine, K. L. Kotloff, J. P. Nataro +1 more

Clinical Infectious DiseasesNov 20, 2012

Open article ↗Gastroenteritis surveillance →

Type: Case-control study
Scope: Bangladesh, Gambia, India

Why it matters nowThe work addresses diarrheal disease, cited as one of the top two causes of young child mortality in the developing world, and aims to inform prioritization of water/sanitation, hygiene, and vaccine strategies.

Peer reviewedOpen accessHaemophilus influenzaePertussisVaccination Climate and environment Vaccine effectiveness

DOI 10.1016/j.vaccine.2006.04.021 ↗

Influence of genetic and environmental factors on the immunogenicity of Hib vaccine in Gambian twins

Y.C. Lee, M.J. Newport, T. Goetghebuer +4 more

VaccineJun 1, 2006

Open article ↗Haemophilus influenzae surveillance →

Type: Journal article
Scope: Gambia

Why it matters nowThe paper is relevant to understanding why Hib vaccine responses may differ between populations and why some vaccinated individuals may have weaker antibody responses. It is an immunogenicity study rather than a direct assessment of disease burden.