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Disease evidence hub

Influenza

A curated view of published Influenza research, auditable classifier relationships, and its publication timeline.

Published evidence
838
Diseases
65
Countries
123
Topics
14

Evidence timeline

Publication timeline

Open disease surveillance →

Monthly publication counts from the catalogue show how research activity changes over time.

24 publication months · peak 2026-08 (42)
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Research Radar publications

Guidance and policy markers identify dated publications in the curated catalogue; they do not by themselves establish that an official policy changed on that date.

Evidence stream

Published literature

838

30 of 838 publications shown

Peer reviewed Open access Influenza Vaccination
DOI 10.3389/fmicb.2026.2002454 ↗

A glycosylation-associated hemagglutinin substitution improves the breadth of an influenza B mRNA vaccine

Ziqi Cheng, Yeqing Sun, Yunbo Bai +2 more

Frontiers in Microbiology

Type
Journal article
Scope
Austria

Why it matters now With no confirmed circulating B/Yamagata-lineage viruses since March 2020, the authors frame B/Victoria protection as the current priority of influenza B vaccination, and the findings are presented as informing broadly protective influenza B vaccine development.

Peer reviewed Open access Influenza
DOI 10.1038/s41467-026-79127-y ↗

Continuous directed evolution using engineered human B cell lines

Stanley Bram, Diego J. Orea, Graeme Lindsey +6 more

Nature Communications

Type
Journal article
Scope
Not classified

Why it matters now The platform may be relevant to rapid antibody and biomolecule development for influenza-related targets, although the supplied abstract does not establish clinical effectiveness, epidemiological utility, or readiness for public-health implementation.

Peer reviewed Open access Influenza Vaccination
DOI 10.3390/jcm15218608 ↗

Influenza Infection, Newly Diagnosed Atrial Fibrillation, and One-Year Mortality in Hospitalized Adults: A Retrospective Cohort Study

Roman Sonkin, Anna Khalemsky, Carmi Bartal

Journal of Clinical Medicine

Type
Cohort study
Scope
Not classified

Why it matters now The findings suggest that, among hospitalized adults tested for respiratory viruses, influenza was not associated with a higher short-term hazard of newly diagnosed atrial fibrillation, while atrial fibrillation identified during hospitalization was associated with increased one-year mortality.

Peer reviewed Open access Influenza Vaccination
DOI 10.3390/jgg74040043 ↗

Influenza Vaccination and Cardiovascular Protection: Current and Emerging Evidence in Primary and Secondary Prevention

Kimia Najafi, Kaveh Hosseini, Tor Biering-Sørensen

Journal of Gerontology and Geriatrics

Type
Journal article
Scope
Not classified

Why it matters now The article identifies influenza vaccination as an increasingly recognized component of cardiovascular disease prevention and secondary prevention frameworks in American and European guidelines.

Peer reviewed Open access Influenza
DOI 10.3389/fpubh.2026.1969113 ↗

Respiratory virus prevalence among healthcare university students in Ecuador: a multicenter cross-sectional study

Alfredo Bruno, Domenica de Mora, Maritza Olmedo +10 more

Frontiers in Public Health

Type
Cross-sectional study
Scope
Ecuador

Why it matters now The low detected prevalence coupled with mostly symptom-free positives suggests potential silent circulation in academic settings, and point-of-care antigen screening appeared operationally practical there.

Transforming pandemic influenza antiviral stockpiling using a capacity-based approach: A modeling study

Nir Gavish, Amit Huppert

PLOS Medicine

Type
Mathematical modelling
Scope
United Kingdom, Japan, United States

Why it matters now The findings indicate that conventional stockpiles sized to cover 25% of a population may be insufficient by themselves during severe pandemics. The authors present capacity-based planning, potentially combining targeted reserves, temporary non-pharmaceutical measures, and flexible care delivery, as an preparedness option to evaluate.

Spatiotemporal variations and influencing factors of highly pathogenic avian influenza risk in the Pan-Tibetan Plateau region

Hongyan Ren, Yao Wang, Runhe Shi

Infectious Diseases of Poverty

Type
Journal article
Scope
Not classified

Why it matters now The abstract frames HPAI as a major infectious disease threatening the poultry industry and public health, and describes the study as contributing to understanding HPAI transmission mechanisms across hosts and to providing a scientific basis for differentiated surveillance in the region.

Effectiveness of maternal influenza vaccine to infants: A population-based cohort study

Yi-Ning Li, Yi-Hsuan Lin, Ching-Heng Lin +1 more

Pediatrics & Neonatology

Type
Cohort study
Scope
Taiwan, China

Why it matters now The findings suggest that vaccinating pregnant women against influenza provides indirect protection to infants too young for their own vaccination, particularly those at highest risk for severe complications.

Differentiating Avian and Seasonal Influenza Viruses in Wastewater by Digital PCR.

Paracchini V, Petrillo M, Leon FM +13 more

Emerging infectious diseases

Type
Journal article
Scope
Italy

Why it matters now The approach is framed in the context of global health risks posed by highly pathogenic avian influenza A(H5Nx), clade 2.3.4.4b, and offers a tool to improve environmental influenza surveillance.

Peer reviewed Open access SARSCOVID-19 SurveillanceTravel medicine
DOI 10.1016/j.meegid.2026.106036 ↗

Aircraft wastewater virome surveillance from domestic and international flights reveals viral diversity among travellers: A proof-of-concept study from Gujarat, India

Nitin Shukla, Nimesh Patel, Jinal Thakor +9 more

Infection, Genetics and Evolution

Type
Journal article
Scope
India

Why it matters now The authors suggest that ongoing airport wastewater monitoring may offer early alerts to health agencies and support coordinated response, pending cross-border cooperation.

Peer reviewed Open access SARSCOVID-19 Vaccination
DOI 10.1038/s41598-026-75831-3 ↗

Vaccination rates, facilitators and barriers for influenza, pneumococcal and SARS-CoV-2 vaccination among sepsis survivors: a Mid-German Sepsis Cohort survey

Carl Zimmermann, Sebastian Born, Norman Rose +4 more

Scientific Reports

Type
Journal article
Scope
Germany

Why it matters now The authors describe considerable vaccination gaps in sepsis survivors and identify general-practitioner counselling and vaccination-status checks as potential elements of sepsis aftercare.

Peer reviewed Open access InfluenzaH5N1 Genomic epidemiologyOne Health
DOI 10.1128/jvi.01372-26 ↗

Bovine myxovirus resistance protein (Mx)1, but not Mx2, mediates antiviral activity against human and avian influenza A viruses, including H5N1 clade 2.3.4.4b

Rubaiyea Farrukee, Yongyan Xia, Rachel Morris +9 more

Journal of Virology

Type
Genomic study
Scope
United States

Why it matters now The work indicates continued H5N1 circulation in cows may allow viral changes that evade Mx defenses, potentially raising spillover or pandemic risk.

Update to the CDC influenza A(H3) subtyping assay for improved detection of influenza A(H3N2) viruses, including subclade K viruses

Bo Shu, Jimma Liddell, Phili Wong +9 more

Journal of Clinical Microbiology

Type
Journal article
Scope
Not classified

Why it matters now Reliable subtyping of A(H3N2), including drifted and subclade K viruses, supports diagnostic preparedness and influenza surveillance capacity nationally and internationally.

Spatial Distribution and Genetic Diversity of Highly Pathogenic Avian Influenza A (H5N1) in Bulgaria, 2024–2026

Gabriela Goujgoulova, Koycho Koev

Life

Type
Genomic study
Scope
Bulgaria

Why it matters now Linking spatial, temporal, and genetic monitoring may help locate high-risk areas and reinforce control of HPAI in Bulgaria.

Peer reviewed Open access COVID-19Influenza Surveillance
DOI 10.1186/s12879-026-14610-x ↗

Detection profiles and co-detection patterns of respiratory pathogens in hospitalized patients with acute respiratory infections after the COVID-19 pandemic in Nantong, China

Ting Wu, Wen Liao, Jianguo Zhang +1 more

BMC Infectious Diseases

Type
Cross-sectional study
Scope
China

Why it matters now Age- and season-specific peaks suggest value in tailoring surveillance by school-age and winter periods, per the authors' stated support for informed monitoring.

Epidemiological characterization of avian influenza virus circulation in pigeons and quail across different production systems in Chattogram, Bangladesh

Mohammad Iqbal Habib, Md Abu Sayeed, Monjurul Islam +6 more

PLOS One

Type
Cross-sectional study
Scope
Bangladesh

Why it matters now The authors argue these understudied species may sustain virus transmission in mixed systems, so including them in routine monitoring could aid early detection and spillover reduction.

Impact of low temperature on the efficacy of chlorous acid water and sodium hypochlorite solution for inactivating avian influenza virus on material surfaces

Tomoko Morita, Abeer Mohamed Abdelfattah Elsayed, Rie Hirakawa +9 more

PLOS One

Type
Journal article
Scope
Not classified

Why it matters now The results suggest chlorous acid water could be useful in real-world low-temperature poultry settings, though the abstract stops at suggesting potential utility.

Peer reviewed Open access COVID-19Influenza Vaccination
DOI 10.1017/s0950268826102180 ↗

An investigation into post-pandemic ethnic group and deprivation inequalities in influenza and COVID-19 hospitalizations.

Scott M, Browning L, Roberts T +3 more

Epidemiology and infection

Type
Journal article
Scope
Bangladesh

Why it matters now Improving vaccination coverage in under-vaccinated groups is highlighted as a continuing public health priority based on the mediation results.

Respiratory syncytial virus in adults aged ≥ 50 years in the Netherlands: a database and time-series modelling analysis (2013–2020)

Rachel M. Reeves, Sonya Parmar, Saskia Hagenaars +12 more

Infection

Type
Cohort study
Scope
Netherlands

Why it matters now The documented hospital load supports prioritising RSV prevention, such as vaccination, within older adult programmes alongside influenza control.

Peer reviewed Open access Influenza Surveillance
DOI 10.63158/journalisi.v8i5.1860 ↗

Forecasting Weekly Influenza Detections in South Africa Using SARIMA and LSTM Models

Ebelechukwu Ajuka, Ebenezer Esenogho, Cameron Modisane

Journal of Information Systems and Informatics

Type
Journal article
Scope
South Africa

Why it matters now More accurate influenza forecasting from surveillance data may support seasonal preparedness using nearly three decades of recorded detections.

Peer reviewed Open access InfluenzaCOVID-19 Climate and environment
DOI 10.1088/2752-5309/aeb0c4 ↗

Climate-informed short-term forecasting of influenza incidence in Australia

Aminath Shausan, Vassili Kitsios, Hwan-Jin Yoon +2 more

Environmental Research: Health

Type
Journal article
Scope
Australia

Why it matters now Skilful climate-informed forecasts may aid early warning and preparedness, offering operationally relevant support for public health planning in Australia.

Broadly reactive antibodies against influenza B virus hemagglutinin neutralize and protect through distinct structural mechanisms

Disha Bhavsar, Alesandro Civljak, Bruno Bonnettaz +3 more

Journal of Virology

Type
Journal article
Scope
Not classified

Why it matters now Findings clarify correlates of immune protection and may inform design of broadly protective influenza B vaccines and antibody therapies.

Interaction between DEAD-box RNA helicase 10 and influenza PB1 polymerase selectively regulates influenza A virus replication

Rizwan Ullah, Wei Chen, Lingkai Zhang +9 more

Journal of Virology

Type
Journal article
Scope
Not classified

Why it matters now The authors state the results may aid prediction of cross-species transmission potential and host-targeted antiviral design, based on the identified molecular interface.

Peer reviewed Open access Influenza One Health
DOI 10.1128/jvi.01265-26 ↗

Antigenic and structural analysis of the influenza hemagglutinin lateral patch

Jordan I. Lemus-Reyes, Monica L. Fernández-Quintero, Edgardo Ayala +7 more

Journal of Virology

Type
Journal article
Scope
Not classified

Why it matters now Conservation of the lateral patch among animal and human H1Nx viruses suggests it may be a useful target for preparedness against emergent pandemic strains.

Developing and benchmarking one health genomic surveillance tools for influenza A virus in wastewater

Minxi Jiang, Audrey L. W. Wang, James B. Thissen +3 more

Nature Communications

Type
Journal article
Scope
Not classified

Why it matters now Optimizing genomic sequencing techniques for wastewater enhances the capacity to monitor Influenza A viruses within a One Health framework. These methodological improvements support the routine tracking of diverse and potentially emerging viral subtypes in environmental samples.

Peer reviewed Open access InfluenzaHIV infection VaccinationVaccine effectivenessTreatment
DOI 10.3389/fimmu.2026.1945123 ↗

Immunogenicity and safety of trivalent inactivated influenza vaccine in adults living with HIV compared with HIV-uninfected adults: a study from China

Jinfeng Su, Kai Gao, Shasha Han +15 more

Frontiers in Immunology

Type
Journal article
Scope
China

Why it matters now The observed safety profile and substantial, albeit strain-variable, antibody production reinforce current immunization guidelines for people living with HIV. This data aids in shaping regional vaccination strategies for vulnerable populations.

Peer reviewed Open access InfluenzaToxic shock syndrome SurveillanceGenomic epidemiologyTreatment
DOI 10.3390/microorganisms14102373 ↗

Fatal Post-Influenza Streptococcal Toxic Shock Syndrome Caused by M1UK Streptococcus pyogenes in South Korea: A Case Report

Hae Seong Jeong, Yong Jun Kwon, Mihee Kim +3 more

Microorganisms

Type
Genomic study
Scope
South Korea

Why it matters now The emergence of this specific bacterial lineage in the region underscores the importance of ongoing genomic monitoring for invasive streptococcal infections. It also emphasizes the clinical necessity of evaluating for toxic shock syndrome in individuals presenting with shock subsequent to viral respiratory illnesses.

Peer reviewed Open access Influenza VaccinationTreatment
DOI 10.1128/mbio.01435-26 ↗

Sex and age differences in antibody responses to seasonal influenza vaccination are mediated by estrogenic upregulation of NF-κB and TNF signaling in B cells

Han-Sol Park, Anna Yin, Weiqiang Zhou +16 more

mBio

Type
Journal article
Scope
Not classified

Why it matters now The results indicate hormonal environment influences vaccine-induced immunity beyond chronological age. This may inform understanding of variable influenza vaccine responses across sex and age groups.

Avian influenza A virus polymerase gene leads to temperature-resistant genome replication

Stephanie L. Williams, Sebastian M. Gygli, Jacob C. Bjorgen +9 more

Journal of Virology

Type
Journal article
Scope
Not classified

Why it matters now The findings identify temperature-tolerant replication as a possible adaptive property of avian-origin PB1 genes. The abstract states that this could inform assessment of zoonotic adaptation and countermeasure development, but it does not establish human transmission risk or pandemic potential for a circulating strain.

Peer reviewed Open access Influenza Vaccination
DOI 10.1093/ofid/ofag646 ↗

Humoral Immunogenicity of mRNA-1010, an mRNA-Based Seasonal Influenza Vaccine, in Adults ≥50 Years

Isabel Leroux-Roels, Elissa Malkin, HuiLing Chen +5 more

Open Forum Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters now The findings provide comparative immunogenicity evidence for mRNA-1010 as a seasonal influenza vaccine candidate in adults aged 50 years or older. The abstract reports antibody outcomes rather than direct clinical effectiveness, disease, hospitalization, or mortality outcomes.