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Peer reviewedOpen accessChikungunya

Specialist laboratory networks as preparedness and response tool - the Emerging Viral Diseases-Expert Laboratory Network and the Chikungunya outbreak, Thailand, 2019

Eurosurveillance·

Giulietta Venturi, Stephan W Aberle, Tatjana Avšič-Županc, Luisa Barzon, Christoph Batejat, Elisa Burdino, Fabrizio Carletti, Rémi Charrel, Iva Christova, Jeff Connell, Victor Max Corman, Mary Emmanouil, Anne J Jääskeläinen, Ivan Kurolt, Yaniv Lustig, Miguel J Martinez, Marion Koopmans, Orsolya Nagy, Trung Nguyen, Anna Papa, Mercedes Pérez-Ruiz, Martin Pfeffer, Jelena Protic, Johan Reimerink, Giada Rossini, María Paz Sánchez-Seco Fariñas, Jonas Schmidt-Chanasit, Sandra Söderholm, Bertrand Sudre, Marjan Van Esbroeck, Chantal B Reusken

DOI
10.2807/1560-7917.es.2020.25.13.1900438
PMID
32265004
PMCID
PMC7140599
OpenAlex
W3014686397
Study type
Journal article
Publisher
European Centre for Disease Control and Prevention (ECDC)
Article type
journal-article
Integrity
current

Why this research matters now

The report illustrates how a specialist laboratory network can consolidate diagnostic and sequence data across countries to support outbreak situational awareness, while noting that preparedness impact depends on further standardisation of data collection and quality.

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Structured evidence summary

Research question

The paper examines whether a specialist laboratory network can function as a preparedness and response tool by rapidly collecting and sharing data during an outbreak, using the 2019 chikungunya outbreak in Thailand and related imported cases as a case study.

Study design

A descriptive report describing network-based data collection across the Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet), capturing laboratory requests, diagnosed imported chikungunya cases, and viral sequences during a defined comparison period.

Population and setting

The setting is the EVD-LabNet network of specialist laboratories, with the population comprising returning European travellers diagnosed with chikungunya virus infection, particularly those with reported travel to Thailand. The observation window covers 1 October 2018 to 30 April 2019, compared with the same period in 2018.

Main findings

Imported chikungunya cases reported across the network rose from 50 to 172 between the two comparison periods, with travel to Thailand increasing from 1 to 72 cases. Diagnostic requests rose by 23.6% between the two periods. Sequence data from Thailand-imported strains clustered with the ECSA-IOL E1 A226 variant linked to outbreaks in Pakistan (2016) and Italy (2017).

Public-health relevance

The report illustrates how a specialist laboratory network can consolidate diagnostic and sequence data across countries to support outbreak situational awareness, while noting that preparedness impact depends on further standardisation of data collection and quality.

Important limitations

The authors indicate that the network's utility as a preparedness and response tool is constrained by the current lack of standardisation in how laboratories collect, quality-check, and mine data within routine management systems.

GIDS interpretation

Within GIDS, the abstract is discoverable under chikungunya, diagnostics, outbreak investigation, surveillance, and travel medicine, with links to Thailand, Italy, and Pakistan; its relevance to any live surveillance signal would need to be assessed against the original paper rather than inferred here.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 11 auditable classifier relationships to diseases, places, topics, and study design.

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