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疾病概览

病毒性

寨卡病毒病

Zika virus disease

有证据支持的资料英文 5/7 个适用章节 · 中文 5/7 个适用章节更新于 2026年9月3日

寨卡病毒病是由寨卡病毒引起的一种蚊媒传染病,主要通过伊蚊属(尤其是埃及伊蚊)叮咬传播,在热带和亚热带地区呈地方性流行[1][2]。多数感染者无症状或仅有轻微症状,但孕期感染可导致新生儿小头症及其他先天性畸形(统称为先天性寨卡综合征),成人感染还与格林-巴利综合征发病增加相关[1][2][3]。自2015年在巴西暴发大规模疫情后,全球报告病例自2017年起显著下降,但寨卡病毒仍在美洲及其他流行区以低水平持续传播,且仍可在新地区引发局部暴发[1][2][4]

阅读完整临床与流行病学资料6
定义

寨卡病毒是一种属于黄病毒科(Flaviviridae)的蚊媒病毒,最早于1947年在乌干达从恒河猴中分离,随后在非洲和亚洲引起散在人类感染[2][5]。该病毒主要通过伊蚊属蚊虫叮咬传播,也可经由母婴垂直传播、性接触、实验室暴露以及血液和血制品输注等非蚊媒途径传播[1][2]

临床特征

大多数寨卡病毒感染者不出现明显症状;在发病者中,潜伏期估计为3–14天,常见症状包括皮疹、发热、结膜炎、肌肉和关节疼痛、不适和头痛,通常持续2–7天[1]。孕期感染寨卡病毒可导致婴儿先天性寨卡综合征,表现为小头症、四肢挛缩、肌张力增高、眼部异常和听力损失,并可引起胎儿丢失、死产和早产等不良结局[2]。成人感染还与格林-巴利综合征发病率升高相关[2][3]。实验室确诊需通过RT-PCR检测病毒RNA或IgM抗体检测,并需与其他黄病毒(如登革病毒)进行鉴别[2]

流行病学

寨卡病毒于1947年首次在乌干达被发现,20世纪60至80年代在非洲和亚洲报告散在病例[2]。自2007年起,非洲、美洲、亚洲和太平洋地区相继记录到寨卡病毒病暴发;2015年巴西发生大规模疫情,引发美洲广泛传播[2]。2016年2月至11月,世卫组织就小头症、其他神经系统疾病与寨卡病毒宣布国际关注的突发公共卫生事件[1][2]。自2017年起全球报告病例明显下降,但美洲多个国家及其他流行区仍存在低水平传播,2019年欧洲首次报告本地蚊媒传播病例[1][2]

传播/暴露

寨卡病毒主要经由热带和亚热带地区的伊蚊属(以埃及伊蚊为主)叮咬传播,这些蚊虫白天活动,清晨和傍晚为叮咬高峰[1]。除蚊媒传播外,寨卡病毒还可通过母婴(孕期)、性接触、实验室暴露以及血液和血制品输注传播,器官移植也被认为是潜在的传播途径[1][2]。伊蚊同时也是登革病毒、基孔肯雅病毒以及城市型黄热病毒的传播媒介[1]

预防

由于目前尚无获批的寨卡病毒疫苗或特效治疗,预防策略主要侧重于避免蚊虫叮咬[1][3]。防控措施包括防蚊(使用驱蚊剂、穿长袖衣物、使用蚊帐)、消除蚊虫孳生地以及在流行地区提供防护指导[1][3]。安全性行为(如使用避孕套)也被建议用于预防可能的性传播,尤其针对从流行地区返回的男性及其伴侣[1]。多种寨卡疫苗仍处于不同临床研发阶段,但3期试验尚需等待下一次流行才能推进[4]

参考文献
  1. 1World Health Organization. Zika virus [Internet]. cited 3 Sept 2026.Available from: https://www.who.int/news-room/fact-sheets/detail/zika-virus
  2. 2Giraldo MI et al. Pathogenesis of Zika Virus Infection. Annu Rev Pathol. 2023 Jan 24. PMID: 36151059. doi: 10.1146/annurev-pathmechdis-031521-034739.PubMed: https://pubmed.ncbi.nlm.nih.gov/36151059/
  3. 3Plourde AR et al. A Literature Review of Zika Virus. Emerg Infect Dis. 2016 Jul. PMID: 27070380. doi: 10.3201/eid2207.151990.PubMed: https://pubmed.ncbi.nlm.nih.gov/27070380/
  4. 4World Health Organization. Zika virus disease [Internet]. cited 3 Sept 2026.Available from: https://www.who.int/health-topics/zika-virus-disease
  5. 5de Jong HK et al. Zika virus: an overview update. Curr Opin HIV AIDS. 2025 May 1. PMID: 40048580. doi: 10.1097/COH.0000000000000926.PubMed: https://pubmed.ncbi.nlm.nih.gov/40048580/
编码登记
ICD-10
A92.5
ICD-11
1D47
核心统计
累计病例
495K
峰值月份
2016-03
覆盖区间
38 个报告国家 · 2013-01-01 → 2026-09-01

数据覆盖

报告国家和地区

38 个国家/地区

月度变化趋势

研究雷达

近期相关研究

查看全部研究 →

文献链接仅用于发现研究,不会改变或验证上方的监测序列。

数据获取

本页面数据索引,含来源链接和更新信息。

行数3,150
更新2026-09-01
范围
分块4
来源33 序列 · 990 观测
官方数据来源机构、频率与说明45
Austria

Austria AGES Radar for Infectious Diseases

Austria

来源
每月official_monthly_csv

AGES Radar monthly national source. Internal ingestion retains native categories; public release is disabled pending licence review.

Belgium

ECDC Surveillance Atlas — Belgium Annual Baseline

Belgium

来源
每年official_ecdc_rest_aggregate

Belgium annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Brazil

Brazil DATASUS SINAN

Brazil

来源
每月ftp_dbc

Brazil Ministry of Health DATASUS/SINAN public DBC microdata aggregated to national monthly notification counts.

Switzerland

Switzerland FOPH IDD

Switzerland

来源
每周rest_api

Switzerland FOPH/BAG IDD mandatory reporting API normalized to national case rows. Monthly series may use the dashboard CHFL aggregate where CH-only monthly series are not exposed.

China

China CDC Weekly

China

来源
MONTHLY网页

Monthly notifiable infectious disease reports published by China CDC.

China

National Disease Control and Prevention Administration

China

来源
MONTHLY网页

Official China public health bulletin and query portal.

China

PubMed

China

来源
MONTHLY网页

Biomedical literature discovery feed used as supplementary context.

Cyprus

ECDC Surveillance Atlas — Cyprus Annual Baseline

Cyprus

来源
每年official_ecdc_rest_aggregate

Cyprus annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Czechia

ECDC Surveillance Atlas — Czechia Annual Baseline

Czechia

来源
每年official_ecdc_rest_aggregate

Czechia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Germany

Germany RKI SurvStat 2.0

Germany

来源
每周official_webforms_csv_export

RKI SurvStat national weekly notification export; raw ZIP exports are retained and recent weeks are overwritten for revisions.

Denmark

ECDC Surveillance Atlas — Denmark Annual Baseline

Denmark

来源
每年official_ecdc_rest_aggregate

Denmark annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Estonia

ECDC Surveillance Atlas — Estonia Annual Baseline

Estonia

来源
每年official_ecdc_rest_aggregate

Estonia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Spain

ECDC Surveillance Atlas — Spain Annual Baseline

Spain

来源
每年official_ecdc_rest_aggregate

Spain annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Finland

Finland THL Infectious Diseases Register

Finland

来源
每月cube_csv

Finland THL Infectious Diseases Register national monthly case counts. The current month is ingested as provisional and the latest three months are refreshed for source revisions.

France

ECDC Surveillance Atlas — France Annual Baseline

France

来源
每年official_ecdc_rest_aggregate

France annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

United Kingdom

ECDC Surveillance Atlas — United Kingdom Annual Baseline

United Kingdom

来源
每年official_ecdc_rest_aggregate

United Kingdom annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Greece

ECDC Surveillance Atlas — Greece Annual Baseline

Greece

来源
每年official_ecdc_rest_aggregate

Greece annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Hong Kong, China

Hong Kong, China CHP Notifiable Diseases

Hong Kong, China

来源
每月开放数据

Hong Kong, China CHP annual notifiable infectious disease CSVs normalized to national monthly totals

Croatia

ECDC Surveillance Atlas — Croatia Annual Baseline

Croatia

来源
每年official_ecdc_rest_aggregate

Croatia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Hungary

ECDC Surveillance Atlas — Hungary Annual Baseline

Hungary

来源
每年official_ecdc_rest_aggregate

Hungary annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Ireland

Ireland HPSC Notifiable Diseases Hub

Ireland

来源
每周official_arcgis_feature_service

Ireland HPSC national weekly notifiable-disease totals from the official ArcGIS FeatureServer. Internal ingestion is enabled; public release remains disabled pending written redistribution permission.

Iceland

冰岛卫生署年度传染病看板

Iceland

来源
每年Power BI 看板

冰岛全国分病种年度病例通报;历史值可能追溯修订,并保持年度总量口径。

Iceland

冰岛卫生署性病监测看板

Iceland

来源
月度事实(按季度发布)Power BI 看板

实验室与登记监测的月度性病诊断事实;官方看板按季度发布。

Iceland

冰岛卫生署呼吸道感染周度看板

Iceland

来源
每周Power BI 看板

按 ISO 周记录的呼吸道疾病诊断数;住院、样本和疫苗指标不计入诊断数。

Iceland

冰岛卫生署历史传染病登记

Iceland

来源
年度与月度官方 Excel

1997—2021 年官方历史登记表,年度与月度事实按原始粒度保留。

Iceland

冰岛卫生署历史 ICD 临床月报

Iceland

来源
每月官方 Excel

Saga 电子病历 ICD 就诊数;与登记通报不可比并保持独立。

Italy

ECDC Surveillance Atlas — Italy Annual Baseline

Italy

来源
每年official_ecdc_rest_aggregate

Italy annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Japan

日本 NIID/JIHS 周报

Japan

来源
每周网页

日本 NIID/JIHS 周度传染病监测数据。

South Korea

Korea KDCA EID

South Korea

来源
每月open_api_or_portal_download

Korea KDCA notifiable infectious disease OpenAPI or portal/KOSIS downloads aggregated to national monthly notification counts.

Liechtenstein

ECDC Surveillance Atlas — Liechtenstein Annual Baseline

Liechtenstein

来源
每年official_ecdc_rest_aggregate

Liechtenstein annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Lithuania

ECDC Surveillance Atlas — Lithuania Annual Baseline

Lithuania

来源
每年official_ecdc_rest_aggregate

Lithuania annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Luxembourg

ECDC Surveillance Atlas — Luxembourg Annual Baseline

Luxembourg

来源
每年official_ecdc_rest_aggregate

Luxembourg annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Latvia

ECDC Surveillance Atlas — Latvia Annual Baseline

Latvia

来源
每年official_ecdc_rest_aggregate

Latvia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Malta

ECDC Surveillance Atlas — Malta Annual Baseline

Malta

来源
每年official_ecdc_rest_aggregate

Malta annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Netherlands

ECDC Surveillance Atlas — Netherlands Annual Baseline

Netherlands

来源
每年official_ecdc_rest_aggregate

Netherlands annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Norway

Norway FHI MSIS Statistics Bank

Norway

来源
每月official_json_api

Norway FHI MSIS national monthly notifications from the official Allvis frontend API; adapter contract checks guard the unversioned endpoint.

Portugal

ECDC Surveillance Atlas — Portugal Annual Baseline

Portugal

来源
每年official_ecdc_rest_aggregate

Portugal annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Romania

ECDC Surveillance Atlas — Romania Annual Baseline

Romania

来源
每年official_ecdc_rest_aggregate

Romania annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Sweden

Sweden Public Health Agency SmiNet

Sweden

来源
每月official_html_csv

Sweden SmiNet national monthly reported cases from the official Public Health Agency statistics pages; public release is enabled with closed-month publication and revisable recent-month refreshes.

Singapore

Singapore CDA Weekly Infectious Diseases Bulletin

Singapore

来源
每周official_csv_and_workbook

Singapore national weekly case notifications, combining the official data.gov.sg 2012–2022 CSV history with CDA annual workbooks from 2023 onward; 2023 weekly PDFs are retained as a source fallback.

Slovenia

ECDC Surveillance Atlas — Slovenia Annual Baseline

Slovenia

来源
每年official_ecdc_rest_aggregate

Slovenia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Slovakia

ECDC Surveillance Atlas — Slovakia Annual Baseline

Slovakia

来源
每年official_ecdc_rest_aggregate

Slovakia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.

Taiwan, China

Taiwan, China CDC NIDSS

Taiwan, China

来源
每月开放数据

Taiwan, China monthly notifiable infectious disease open-data CSV feed.

United States

US CDC NNDSS

United States

来源
mixed_weekly_annual接口

CDC National Notifiable Diseases Surveillance System provisional data.

United States

US CDC NHSS HIV

United States

来源
mixed_weekly_annual接口

CDC NNDSS weekly data plus NHSS annual national HIV diagnoses

分块公开数据

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