The response to re-emergence of yellow fever in Nigeria, 2017
International Journal of Infectious Diseases·
- DOI
- 10.1016/j.ijid.2019.12.034
- PMID
- 31935537
- PMCID
- —
- OpenAlex
- W3000176189
- Study type
- Outbreak investigation
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The outbreak prompted intensified yellow fever surveillance nationwide, reactive vaccination and social mobilization in affected areas, and initiation of a state-wide preventive campaign in Kwara State.
Structured evidence summary
Research question
The article describes the response to the re-emergence of yellow fever in Nigeria in 2017, following a confirmed case after 21 years without detection.
Study design
Outbreak investigation with active case search conducted between September 18 and October 6, 2017, including laboratory confirmation, vaccination coverage assessment, and entomological survey.
Population and setting
The investigation focused on Ifelodun Local Government Area and five contiguous LGAs in Kwara State, Nigeria. The index case occurred in a nomadic population with historically low yellow fever vaccination uptake.
Main findings
Following the index case, active surveillance identified 55 additional suspect cases with a median age of 15 years. Laboratory testing confirmed yellow fever in nine of 30 tested samples by Nigerian laboratories, with six confirmed by the WHO reference laboratory in Dakar. Vaccination coverage in affected areas was 46 percent, with only 25 percent of cases able to provide vaccination cards. All life stages of Aedes mosquitoes were detected with high larval indices.
Public-health relevance
The outbreak prompted intensified yellow fever surveillance nationwide, reactive vaccination and social mobilization in affected areas, and initiation of a state-wide preventive campaign in Kwara State.
Important limitations
This summary relies on the supplied single-article abstract and metadata. Full interpretation of study limitations, case definitions, laboratory methods, and completeness of the active case search requires review of the original paper.
GIDS interpretation
The article documents an outbreak investigation response following re-emergence of yellow fever after two decades. The classifier links associate the paper with yellow fever, Nigeria, outbreak investigation, surveillance, and vaccination topics, supporting discoverability for retrospective outbreak reviews and vaccination program evaluation.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 13 auditable classifier relationships to diseases, places, topics, and study design.