Yellow Fever Virus in Haemagogus leucocelaenus and Aedes serratus Mosquitoes, Southern Brazil, 2008
Emerging Infectious Diseases·
- DOI
- 10.3201/eid1612.100608
- PMID
- 21122222
- PMCID
- PMC3294583
- OpenAlex
- W2120744233
- Study type
- Journal article
- Publisher
- Centers for Disease Control and Prevention (CDC)
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The findings provide entomologic evidence relevant to yellow fever outbreak investigation and to surveillance activities intended for early virus detection. The abstract also places the work in the context of vaccination program support, without reporting vaccination effectiveness or population-level outcomes.
Structured evidence summary
Research question
The study examined whether yellow fever virus was present in mosquitoes collected during the 2008 outbreak in two municipalities in southern Brazil where nonhuman primate deaths had occurred, and which mosquito taxa carried the virus.
Study design
This was an entomologic surveillance investigation. Mosquitoes were collected, taxonomically identified, tested for virus isolation, and selected viral strains underwent molecular sequencing.
Population and setting
The investigation covered mosquitoes collected at ground level in two municipalities in Rio Grande do Sul State, southern Brazil, during the 2008 yellow fever outbreak. The collection sites were municipalities with reported nonhuman primate deaths.
Main findings
Eight yellow fever virus strains were isolated: seven from Haemagogus leucocelaenus mosquito pools and one from an Aedes serratus pool. Six sequenced strains belonged to the South American genotype I; the abstract identifies Haemagogus leucocelaenus as the principal vector in this setting and describes Aedes serratus as a possible secondary vector.
Public-health relevance
The findings provide entomologic evidence relevant to yellow fever outbreak investigation and to surveillance activities intended for early virus detection. The abstract also places the work in the context of vaccination program support, without reporting vaccination effectiveness or population-level outcomes.
Important limitations
The reported investigation was limited to mosquitoes collected in two municipalities during a specific outbreak, and the abstract does not provide broader geographic coverage, comparative vector estimates, or population-level outcomes. This summary also relies only on the supplied single-article abstract and metadata; the original paper is required for decision-grade interpretation.
GIDS interpretation
The supplied metadata classifies the article under yellow fever, Brazil, outbreak investigation, surveillance, and vaccination, making it discoverable as an entomologic outbreak-context paper. These classifications describe the article's subject context only and do not confirm a current surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 11 auditable classifier relationships to diseases, places, topics, and study design.