COVID-19 vaccine perceptions and uptake in a national prospective cohort of essential workers
Vaccine·
- DOI
- 10.1016/j.vaccine.2021.11.094
- PMID
- 34906392
- PMCID
- PMC8665770
- OpenAlex
- W4226055236
- Study type
- Cohort study
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Publication version
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Open linked preprint →Why this research matters now
The abstract provides evidence about vaccine perceptions and uptake patterns in an essential-worker cohort, including differences by occupation, prior infection, and initial vaccine intention. It also reports changes in vaccine-related responses between survey administrations, which may be relevant to research on vaccine acceptance in similar populations.
Structured evidence summary
Research question
The study examined how COVID-19 vaccine knowledge, attitudes, practices, intention, prior SARS-CoV-2 infection, and occupation related to vaccine uptake over time among essential workers.
Study design
This was a multicenter prospective cohort analysis using two follow-up surveys conducted approximately three months apart, with vaccination data collected through May 2021.
Population and setting
The analysis included 4,803 essential workers in the national HEROES-RECOVER cohort, initiated in July 2020. Participants were assessed by occupation, prior SARS-CoV-2 infection, vaccine intention, and vaccination status.
Main findings
Most participants were classified as vaccine endorsers (70%), while 16% were reachable and 14% were reluctant; 77% had received at least one dose by May 2021. Positive views of vaccine safety and effectiveness were associated with higher uptake, and uptake between surveys differed across intention groups: 25% among reluctant participants, 56% among reachable participants, and 83% among endorsers. Participants with prior SARS-CoV-2 infection and first responders were less likely to view the vaccine as effective than their respective comparison groups.
Public-health relevance
The abstract provides evidence about vaccine perceptions and uptake patterns in an essential-worker cohort, including differences by occupation, prior infection, and initial vaccine intention. It also reports changes in vaccine-related responses between survey administrations, which may be relevant to research on vaccine acceptance in similar populations.
Important limitations
The supplied evidence does not state specific study limitations. This summary is limited to the supplied single-article abstract and metadata; the original paper is required for decision-grade assessment of sampling, measurement, confounding, missing data, and generalizability.
GIDS interpretation
The article is discoverable as evidence concerning COVID-19 vaccination, vaccine perceptions, vaccine safety and effectiveness, and outbreak-related research. It provides context from one prospective essential-worker cohort and does not establish or confirm any live surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 11 auditable classifier relationships to diseases, places, topics, and study design.