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Spain research

Published infectious-disease research classified with a high-confidence geographic relationship to Spain.

Published evidence
15
Diseases
14
Countries
19
Topics
12

Evidence stream

Published literature

15

15 publications

Tularemia: a re-emerging zoonosis.

Hernández M, Oteo JA, Eiros JM

Medicina clinica

Type
Genomic study
Scope
Austria, Spain, France

Why it matters nowTularemia is classified as a CDC Category A bioterrorism agent due to extreme virulence (infection possible with as few as 10 cells) and 30% mortality in untreated cases. The documented re-emergence across multiple Northern Hemisphere regions underscores the need for updated clinical awareness and early diagnostic capacity.

Peer reviewedOpen accessLeishmaniasisHIV infectionSurveillanceDiagnosticsTreatment
DOI 10.3390/tropicalmed11080235 ↗

Addressing the Gaps and Challenges of Autochthonous Mucocutaneous Leishmaniasis in Spain

Diego Gayoso-Cantero, Begoña Monge-Maillo, Jose A. Perez-Molina

Tropical Medicine and Infectious Disease

Type
Journal article
Scope
Spain

Why it matters nowStrengthening clinician education and integrating standardized protocols into official recommendations may decrease evaluation delays and treatment disparities.

The 1820 Mallorca plague was not a classic bubonic outbreak

Pedro Puig, Joana Maria Pujadas-Mora

Proceedings of the National Academy of Sciences

Type
Journal article
Scope
Spain

Why it matters nowHistorical reconstruction of transmission pathways contributes to scholarly debates regarding plague ecology and the biological characteristics of late pandemic waves.

Peer reviewedInvasive pneumococcal diseaseVaccinationSurveillance
DOI 10.1016/j.vaccine.2026.128940 ↗

Persistent vaccine-type invasive pneumococcal disease in children despite high PCV13 coverage: the role of serotype 3

Pilar Ciruela, Sonia Broner, Fernando Moraga-Llop +13 more

Vaccine

Type
Journal article
Scope
Spain

Why it matters nowThe findings identify serotype 3 and PCR-based diagnosis as prominent features of the reported paediatric PCV13-type invasive pneumococcal disease cases. The abstract also reports that the authors considered molecular diagnostics, ongoing surveillance, and improved serotype 3 protection relevant to this issue.

Autochthonous transmission of dengue in Europe, with special attention to the Spanish context

Marta Bononad Brugger, M. Adela Valero, María Morales-Suárez-Varela

Epidemiology and Infection

Type
Journal article
Scope
Spain

Why it matters nowAutochthonous dengue transmission in southern Europe represents a growing public health concern. The work proposes strategies to strengthen epidemiological surveillance, improve outbreak preparedness, and optimize vector-control policies in the context of global change.

Unveiling the enterovirus diversity in Barcelona, Spain (2020–2024) through wastewater and clinical surveillance

David Garcia-Pedemonte, Albert Carcereny, Cristina Andrés +12 more

Emerging Microbes & Infections

Type
Journal article
Scope
Spain

Why it matters nowWastewater surveillance uncovered greater enterovirus diversity than clinical reporting alone, detecting 56 types not identified through clinical channels. The authors suggest this integrated approach may enable early detection of emerging public health threats and reveal hidden viral diversity missed by routine clinical surveillance.

Outbreak of invasive meningococcal disease caused by a meningococcus serogroup B expressing a rare porA genosubtype (19-54, 15), Spain, March to April 2024

Raquel Abad, Carmen Navarro, Cristina García-Amil +10 more

Eurosurveillance

Type
Journal article
Scope
Spain

Why it matters nowThe report illustrates how surveillance-triggered microbiological and immunological work-up can guide targeted chemoprophylaxis and 4CMenB vaccination among a large contact network, and underscores the need to monitor emergence of the 19-54 genosubtype.

VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment

Jon Salmanton-García, Fiona A. Stewart, Sarah Heringer +48 more

Vaccine

Type
Journal article
Scope
Austria, Belgium, Cyprus

Why it matters nowThe registry addresses a recognized barrier in pandemic response by providing a centralized infrastructure to accelerate clinical trial recruitment across European countries, potentially shortening the timeline for vaccine and treatment development during infectious disease outbreaks.

Health and economic impact of seasonal influenza mass vaccination strategies in European settings: A mathematical modelling and cost-effectiveness analysis

Frank G. Sandmann, Edwin van Leeuwen, Sibylle Bernard-Stoecklin +21 more

Vaccine

Type
Mathematical modelling
Scope
Spain, France, Ireland

Why it matters nowDespite existing vaccination programs targeting older adults and high-risk groups, substantial influenza burden persists in Europe. The findings suggest that combined strategies using improved vaccines for the elderly and universal pediatric vaccination may offer direct and indirect protection that is cost-effective across diverse European settings, supporting broader policy considerations for seasonal influenza control.

Effectiveness of mRNA COVID-19 vaccines in preventing SARS-CoV-2 infections and COVID-19 hospitalisations and deaths in elderly long-term care facility residents, Spain, weeks 53 2020 to 13 2021

Clara Mazagatos, Susana Monge, Carmen Olmedo +6 more

Eurosurveillance

Type
Journal article
Scope
Spain

Why it matters nowThe findings support the prioritization of long-term care facility residents for COVID-19 vaccination and demonstrate high effectiveness of mRNA vaccines in this vulnerable population, particularly for preventing severe outcomes.

Whole-genome sequencing of Mycobacterium tuberculosis directly from clinical samples for high-resolution genomic epidemiology and drug resistance surveillance: an observational study

Galo A Goig, Irving Cancino-Muñoz, Manuela Torres-Puente +4 more

The Lancet Microbe

Type
Genomic study
Scope
Spain

Why it matters nowDirect whole-genome sequencing may enable culture-independent, real-time genomic epidemiology and drug resistance surveillance, which could be particularly valuable in settings lacking culture and phenotypic drug susceptibility testing capacity.

Arbovirus surveillance: first dengue virus detection in local Aedes albopictus mosquitoes in Europe, Catalonia, Spain, 2015

Carles Aranda, Miguel J. Martínez, Tomas Montalvo +15 more

Eurosurveillance

Type
Journal article
Scope
Spain

Why it matters nowThe article suggests that entomological monitoring around viraemic travelers may help identify possible local dengue transmission early. In GIDS terms, it is a surveillance-relevant report with context for detectability in a European setting.

West Nile virus-neutralizing antibodies in wild birds from southern Spain

M. FERRAGUTI, J. MARTÍNEZ-DE LA PUENTE, R. SORIGUER +3 more

Epidemiology and Infection

Type
Journal article
Scope
Spain

Why it matters nowThe findings are relevant to arbovirus ecology and bird-based monitoring because birds are described as the main reservoir hosts for WNV. The abstract also places the results in relation to horse-farm occurrence in southern Spain during 2013.

An outbreak of measles in Algeciras, Spain, 2008 – a preliminary report

J Nieto-Vera, J Masa-Calles, J Dávila +4 more

Eurosurveillance

Type
Journal article
Scope
Spain

Why it matters nowThe report highlights the value of regional surveillance networks in early detection and laboratory classification of measles cases, which is relevant to elimination efforts in Spain.

Q Fever in Returned Febrile Travelers: Table 1

Thuy‐Huong Ta, Beatriz Jiménez, Miriam Navarro +3 more

Journal of Travel Medicine

Type
Journal article
Scope
Spain

Why it matters nowThe findings suggest Q fever should be included in differential diagnosis for febrile travelers returning from tropical regions, indicating potential utility in travel-related infectious disease surveillance and clinical decision-making.