Global search

Find data and evidence

Type at least 2 characters. Use arrow keys to review and Enter to open.

Geographic evidence hub

Brazil research

Published infectious-disease research classified with a high-confidence geographic relationship to Brazil.

Published evidence
24
Diseases
13
Countries
10
Topics
11

Evidence stream

Published literature

24

24 publications

Territorial heterogeneity of feline sporotrichosis in an urban endemic setting in southern Brazil during a major flood period

Juliana Maciel Cassali Vieira, Anna Carolina Marques, José Alberto dos Santos +15 more

Preventive Veterinary Medicine

Type
Cross-sectional study
Scope
Brazil

Why it matters nowThe observations highlight how environmental shifts and animal mobility influence pathogen presence in urban environments. Structured monitoring frameworks could assist local health authorities in tracking similar zoonotic trends.

Hearing aids for mild to moderate hearing loss in adults

Melanie A Ferguson, Julia Z Sarant, Rebecca J Bennett +3 more

Cochrane Database of Systematic Reviews

Type
Systematic review
Scope
Australia, Brazil, Hong Kong, China

Why it matters nowFindings align with routine first-line clinical provision of hearing aids to adults seeking help for hearing difficulties, while signalling ongoing uncertainty around benefits for mental health and cognition.

Peer reviewedOpen accessCysticercosisSurveillance
DOI 10.1186/s12879-026-14271-w ↗

Cysticercosis-related benefits in Brazil: an epidemiological analysis of National Institute of Social Security data (2012–2024)

Luciene Costa Lima Rodrigues, Luís Henrique Féres Junqueira Filho, Daniel Barreto de Oliveira +3 more

BMC Infectious Diseases

Type
Cross-sectional study
Scope
Brazil

Why it matters nowThe findings demonstrate that cysticercosis creates a measurable burden on social protection systems through work disability. Administrative social security data may complement traditional surveillance approaches and inform targeted intersectoral policies addressing regional disparities in diagnosis, access to care, and social protection.

Interventions for preventing dengue: a mapping review

Leslie Choi, Bruno Guedes Alcoforado Aguiar, Susi Wisniewski +7 more

Cochrane Database of Systematic Reviews

Type
Systematic review
Scope
Brazil

Why it matters nowThe authors highlight that the main challenge is not a lack of primary studies but the absence of strategic synthesis aligned with decision-making, and call for greater emphasis on epidemiological and implementation outcomes beyond entomological endpoints to support scalable dengue control, particularly in endemic and resource-constrained settings.

Emergence and phylogeography of the dengue vector Aedes aegypti in Southeastern Iran

Jalil Nejati, Mona Koosha, Nayyereh Choubdar +3 more

PLOS Neglected Tropical Diseases

Type
Genomic study
Scope
Iran, Brazil, Mexico

Why it matters nowThe confirmed establishment of genetically diverse Ae. aegypti populations in southeastern Iran represents an emerging invasion corridor that elevates arbovirus transmission risk, including dengue, chikungunya, Zika, and yellow fever. The genetic connectivity with endemic regions in Latin America, Africa, and South Asia underscores the need for integrated vector monitoring and genomic surveillance to inform prevention strategies.

Comparison of phylogenetic metrics of transmission between symptomatic and asymptomatic tuberculosis in individuals who were incarcerated in Brazil in 2008–24: a retrospective genomic epidemiology study

Kesia Esther da Silva, Paulo César Pereira dos Santos, Daniel Henrique Tsuha +11 more

The Lancet Microbe

Type
Cohort study
Scope
Brazil, United States

Why it matters nowExclusive reliance on clinical symptoms for identifying infected persons may overlook a major driver of ongoing dissemination, indicating that systematic screening protocols are essential in congregate environments.

Peer reviewedOpen accessInvasive pneumococcal diseaseVaccinationSurveillance
DOI 10.1016/j.vaccine.2026.128947 ↗

Invasive pneumococcal disease in Latin America: serotype distribution and vaccine coverage among adults in Mexico, Brazil, and Argentina

Amanda Martino, Juan Urrego-Reyes, Jan Cervenka +2 more

Vaccine

Type
Cross-sectional study
Scope
Argentina, Brazil, Mexico

Why it matters nowThe findings provide country- and age-specific estimates of the proportion of adult invasive pneumococcal disease associated with serotypes covered by available vaccines. The analysis indicates that PCV21 had broader estimated serotype coverage than the other vaccines assessed, while the abstract does not measure vaccination-program implementation, vaccine effectiveness, or reductions in disease after vaccination.

Peer reviewedOpen accessChikungunyaDengue
DOI 10.1016/j.ijid.2026.109050 ↗

Characterisation of the clinical forms of chronic chikungunya: an observational cohort study in Rio de Janeiro

Josephine Bourner, Alessandra Dantas do Nascimento, Wim Alexander Fleischmann +8 more

International Journal of Infectious Diseases

Type
Cohort study
Scope
Brazil

Why it matters nowThe substantial proportion of patients experiencing chronic symptoms with functional impact suggests a need for early risk stratification and integration of long-term care protocols into arboviral disease management systems.

Peer reviewedOpen accessDengueChikungunyaSurveillanceDiagnostics
DOI 10.1016/j.ijid.2026.108664 ↗

Predominance of arboviruses in acute encephalitis and Guillain–Barré syndrome: Findings from a prospective cohort in Northeast Brazil

Mateus Santana do Rosário, Maria Paula de Souza Sampaio, Lorena Cunha Martins +30 more

International Journal of Infectious Diseases

Type
Cohort study
Scope
Brazil

Why it matters nowThe findings highlight arboviruses, particularly chikungunya, dengue, and the emerging Oropouche virus, as leading causes of acute neurological syndromes in Brazil. The authors emphasize that integrating multiplex viral panels with arboviral assays is essential for improved diagnosis, and that strengthened surveillance and molecular diagnostics are critical in regions with ongoing arboviral transmission.

Resurgent threat in a changing climate: A 20-year bibliometric analysis of global Chikungunya research evolution and pandemic preparedness

Xiaoyi Xu, Liming Ye, Yawei Liu +2 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil, France, India

Why it matters nowHighlights increasing academic investment in vaccine platforms and climate-linked transmission models. Identifies structural imbalances in multinational research partnerships and recommends aligning pathogen readiness initiatives with broader environmental health planning.

Peer reviewedOpen accessChikungunyaVaccination
DOI 10.1016/j.ijid.2025.108193 ↗

Genetic polymorphisms in the E2 glycoprotein of chikungunya virus (2014-2023) and their potential implications for immunity and vaccine design

Mayanna Moreira Costa Fogaça, Milena Silva Souza, Ruth Dálety da Silva Brito +7 more

International Journal of Infectious Diseases

Type
Journal article
Scope
Brazil

Why it matters nowThe findings may inform assessment of chikungunya vaccine targets and preparedness planning because variation in the E2 glycoprotein could affect interpretation of immune recognition and viral biological functions. The abstract does not establish effects on vaccine effectiveness, transmission, disease severity, or outbreak occurrence.

Leptospirosis in Campinas, Brazil: The interplay between drainage, impermeable areas, and social vulnerability

Thiago Salomão de Azevedo, Shahista Nisa, Stuart Littlejohn +1 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil

Why it matters nowThe authors suggest the results support targeted prevention and control strategies in densely populated urban areas of the Global South and that combining contextual environmental data with spatial analysis can inform public health policy, spatial planning, and future epidemiological models.

Climate change, urbanisation and transmission potential: Aedes aegypti mosquito projections forecast future arboviral disease hotspots in Brazil

Katherine Heath, Lincoln Muniz Alves, Michael B. Bonsall

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil

Why it matters nowThe work is framed as supporting national and sub-national arboviral risk planning and highlighting compounded risks for peri-urban and rural populations that may benefit from integrated climate, vector-control, and equity-oriented interventions.

Chikungunya in a pediatric cohort: Asymptomatic infection, seroconversion, and chronicity rates

Blenda de Jesus Pereira, Michelle Queiroz Aguiar Brasil, Jessica de Jesus Silva +12 more

PLOS Neglected Tropical Diseases

Type
Cohort study
Scope
Brazil

Why it matters nowThe findings indicate that most CHIKV infections in children are symptomatic, a small but notable proportion fail to seroconvert after acute infection, and chronic disease can occur in the pediatric population. These patterns support the need for sustained surveillance and age-appropriate interventions for chikungunya in children and adolescents.

Unraveling regional variability in Dengue outbreaks in Brazil: leveraging the Moving Epidemics Method (MEM) and climate data to optimize vector control strategies

Ayrton Sena Gouveia, Marcelo Ferreira da Costa Gomes, Iasmim Ferreira de Almeida +13 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil

Why it matters nowThe abstract reports that prevention and control activities could be prioritized by regional historical and climatic patterns, beginning with the North-Northwest and Southeast groups and followed by the other identified regions. It also describes possible use alongside monitoring systems and cross-sector coordination, without establishing that this approach improves health outcomes.

Spatial and temporal dynamics of leptospirosis in South Brazil: A forecasting and nonlinear regression analysis

Alessandra Jacomelli Teles, Bianca Conrad Bohm, Suellen Caroline Matos Silva +2 more

PLOS Neglected Tropical Diseases

Type
Ecological study
Scope
Brazil

Why it matters nowThe predictive model can serve as a tool for epidemiological analysis and healthcare service planning. The spatial and temporal clustering findings underscore the need for intersectoral surveillance and community control policies addressing municipal disparities in Brazil.

Reemergence of yellow fever virus in southeastern Brazil, 2017–2018: What sparked the spread?

Joelle I. Rosser, Karin Nielsen-Saines, Eduardo Saad +1 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil

Why it matters nowFindings highlight drought and rural or outdoor exposure as plausible contributors to YFV reemergence in southeastern Brazilian states that had been YFV-free for nearly a century, underscoring environmental and demographic factors relevant to outbreak preparedness.

Spatial epidemiology of yellow fever: Identification of determinants of the 2016-2018 epidemics and at-risk areas in Brazil

Benoit de Thoisy, Natalia Ingrid Oliveira Silva, Lívia Sacchetto +2 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil

Why it matters nowThe study provides an evidence-based framework for describing yellow fever spatial heterogeneity and developing risk maps in Brazil. Its findings indicate that spatial analyses considered by the article included ecological conditions, host-related factors, and social and epidemiological variables rather than climate variables alone.

Haemagogus leucocelaenus and Haemagogus janthinomys are the primary vectors in the major yellow fever outbreak in Brazil, 2016–2018

Filipe Vieira Santos de Abreu, Ieda Pereira Ribeiro, Anielly Ferreira-de-Brito +23 more

Emerging Microbes & Infections

Type
Journal article
Scope
Brazil

Why it matters nowThe study is presented as relevant to identifying receptive areas and informing vaccination planning in affected and exposed populations. It also frames the findings as important for understanding outbreak spread in a region with long-term interruption of viral circulation.

Fatal Yellow Fever in Travelers to Brazil, 2018

Davidson H. Hamer, Kristina Angelo, Eric Caumes +9 more

MMWR. Morbidity and Mortality Weekly Report

Type
Journal article
Scope
Brazil

Why it matters nowThe report underscores the importance of pre-travel yellow fever vaccination for travelers to outbreak-affected regions in Brazil, where the case fatality rate among those with severe illness ranges from 20% to 60%.

Dengue disease outbreak definitions are implicitly variable

Oliver J. Brady, David L. Smith, Thomas W. Scott +1 more

Epidemics

Type
Journal article
Scope
Brazil

Why it matters nowEstablishing precise quantitative thresholds for outbreak identification remains critical for designing effective reactive public health responses. Current policy frameworks require adaptation to reflect local treatment, surveillance, and control capacities to ensure broad applicability.

Prisons as Reservoir for Community Transmission of Tuberculosis, Brazil

Flávia P.C. Sacchi, Renata M. Praça, Mariana B. Tatara +7 more

Emerging Infectious Diseases

Type
Case-control study
Scope
Brazil

Why it matters nowControlling tuberculosis in prison settings is critical for reducing disease prevalence in the broader community, as prisons may serve as reservoirs for community transmission.

Congenital toxoplasmosis and prenatal care state programs

Mariza M Avelino, Waldemar N Amaral, Isolina MX Rodrigues +4 more

BMC Infectious Diseases

Type
Cohort study
Scope
Brazil

Why it matters nowThe findings support the implementation of both primary prevention measures for all pregnant women and secondary prophylaxis through seroconversion surveillance in seronegative pregnant women to reduce the severity of congenital toxoplasmosis in high-incidence settings.

Yellow Fever Virus in Haemagogus leucocelaenus and Aedes serratus Mosquitoes, Southern Brazil, 2008

Jáder da C. Cardoso, Marco A.B. de Almeida, Edmilson dos Santos +11 more

Emerging Infectious Diseases

Type
Journal article
Scope
Brazil

Why it matters nowThe findings provide entomologic evidence relevant to yellow fever outbreak investigation and to surveillance activities intended for early virus detection. The abstract also places the work in the context of vaccination program support, without reporting vaccination effectiveness or population-level outcomes.