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Geographic evidence hub

Malaysia research

Published infectious-disease research classified with a high-confidence geographic relationship to Malaysia.

Published evidence
14
Diseases
21
Countries
21
Topics
12

Evidence stream

Published literature

14

14 publications

Mixing versus matching booster vaccines: A longitudinal humoral immune kinetics against Omicron in a Malaysian cohort

Ashwathy Varadarajan Thundakattil, Rekha Prabhu, Girish Prabhu +12 more

International Journal of Infectious Diseases

Type
Cohort study
Scope
Malaysia

Why it matters nowThe findings offer immunogenicity evidence relevant to booster vaccination strategy decisions during Omicron-era outbreaks, with particular relevance to settings where inactivated virus priming is used.

Strengthening public understanding and prevention of dengue in Malaysia: insights and recommendations based on knowledge, attitudes, and practices toward vector control and vaccination

Asrul Akmal Shafie, Zulkifli Ismail, Ken Yong +3 more

Frontiers in Public Health

Type
Cross-sectional study
Scope
Malaysia

Why it matters nowIdentifying specific informational gaps and behavioral barriers supports the development of focused outreach initiatives. Aligning communication strategies with established community trust networks could enhance engagement with integrated disease management approaches.

Optimizing Dengue Surveillance Thresholds in Malaysia: A Comparative Evaluation of Endemic Channel Approaches

Sarbhan Singh, Nuur Hafizah Md. Iderus, Lonny Chen Rong Qi Ahmad +10 more

Tropical Medicine and Infectious Disease

Type
Journal article
Scope
Malaysia

Why it matters nowRoutine application of the optimized thresholding framework could assist national monitoring programs in balancing alert frequency with detection reliability.

Peer reviewedOpen accessRubellaToxoplasmosisTransmission dynamics
DOI 10.7717/peerj.21632 ↗

Seroprevalence of toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and syphilis infections among pregnant women and infants in Malaysia: a systematic review and meta-analysis

Abdirahman Hussein Elmi, Ahmad Adebayo Irekeola, Hafeez Abiola Afolabi +4 more

PeerJ

Type
Systematic review
Scope
Malaysia

Why it matters nowThe elevated detection rates indicate that routine maternal testing may help identify vulnerable pregnancies and potentially reduce pathogen transfer to offspring.

Outbreak investigation of reemerging chikungunya virus in Malaysia in 2019–2020

Yik-Zheng Lim, Boon-Teong Teoh, Chee-Sieng Khor +13 more

BMC Infectious Diseases

Type
Genomic study
Scope
Malaysia, Bangladesh, China

Why it matters nowTracking these adapted viral lineages helps clarify regional transmission pathways and highlights potential shifts in pathogen behavior affecting community health planning.

Peer reviewedOpen accessHepatitis CHepatitis ETreatment
DOI 10.1186/s12879-026-13741-5 ↗

Time to viral load suppression with 8-week versus 12-week ravidasvir/sofosbuvir regimens among chronic hepatitis C patients in Malaysia: a non-inferiority, randomized clinical trial

Nor Asiah Muhamad, Nor Soleha Mohd Dali, Nur Hasnah Maamor +6 more

BMC Infectious Diseases

Type
Randomised controlled trial
Scope
Malaysia

Why it matters nowThe findings provide treatment-duration evidence from Malaysian adults with chronic hepatitis C and may inform further evaluation of shorter ravidasvir/sofosbuvir regimens. The abstract does not establish programmatic recommendations, population-level effectiveness, or effects on transmission or mortality.

Malaria cases in China acquired through international travel, 2013–2022

Yan Zhu, Angela Cadavid Restrepo, Hai-Bo Wang +5 more

Journal of Travel Medicine

Type
Systematic review
Scope
China, Angola, Ghana

Why it matters nowDespite China achieving malaria-free certification in 2021, imported cases from returned travelers pose an ongoing risk of local transmission and re-introduction. The findings highlight the need to strengthen travel medicine services, including pre-travel prophylaxis and post-travel diagnostic capacity, to consolidate elimination gains.

Updating estimates of Plasmodium knowlesi malaria risk in response to changing land use patterns across Southeast Asia

Ruarai J. Tobin, Lucinda E. Harrison, Meg K. Tully +8 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Indonesia, India, Malaysia

Why it matters nowThe findings may help inform geographic prioritization for P. knowlesi diagnosis, treatment planning, surveillance and sampling, as described by the authors. The abstract also places the work in the context of malaria elimination planning.

The current burden of Japanese encephalitis and the estimated impacts of vaccination: Combining estimates of the spatial distribution and transmission intensity of a zoonotic pathogen

Sean M. Moore

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Bangladesh, China, India

Why it matters nowThe estimates identify countries and populations where the authors project that increased vaccination coverage could have a substantial effect on Japanese encephalitis burden. The abstract also indicates that reported cases and deaths are substantially below the estimated burden in many endemic countries.

Revisiting the taxonomy and evolution of pathogenicity of the genus Leptospira through the prism of genomics

Antony T. Vincent, Olivier Schiettekatte, Cyrille Goarant +12 more

PLOS Neglected Tropical Diseases

Type
Genomic study
Scope
Algeria, France, Japan

Why it matters nowThe findings expand understanding of Leptospira diversity in environmental reservoirs relevant to zoonotic transmission. The identification of new potentially infectious species and insights into virulence evolution may inform future surveillance and risk assessment, though clinical significance remains to be determined.

Nipah virus infection: A review

Aditi, M. Shariff

Epidemiology and Infection

Type
Journal article
Scope
Malaysia

Why it matters nowThe high mortality, potential for geographic spread, community transmission, and lack of effective countermeasures underscore the public health importance of Nipah virus. A One Health approach is necessary for prevention and control given bat-to-human transmission chains.

Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria

Freya M. Shearer, Zhi Huang, Daniel J. Weiss +18 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Indonesia, Cambodia, Laos

Why it matters nowBecause P. knowlesi is often misidentified as human malaria and can cause severe and fatal disease, understanding its distribution is critical for identifying areas where malaria transmission will persist after human malarias are eliminated. The map provides an initial evidence base for surveillance prioritization in malaria-eliminating countries.

Neglected Tropical Diseases among the Association of Southeast Asian Nations (ASEAN): Overview and Update

Peter J. Hotez, Maria Elena Bottazzi, Ulrich Strych +4 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Indonesia, Cambodia, Myanmar

Why it matters nowThe article identifies urgent needs to expand surveillance activities and ensure mass drug administration for populations at risk for intestinal helminth infections, fluke infections, lymphatic filariasis, trachoma, and yaws, while referencing the ASEAN Network for Drugs, Diagnostics, Vaccines, and Traditional Medicines Innovation as a policy framework for developing new control tools.

The Effect of Vaccination Coverage and Climate on Japanese Encephalitis in Sarawak, Malaysia

Daniel E. Impoinvil, Mong How Ooi, Peter J. Diggle +5 more

PLoS Neglected Tropical Diseases

Type
Journal article
Scope
Malaysia

Why it matters nowThe study offers an improved estimate of vaccination impact on JE by accounting for climatic drivers, suggesting that prior evaluations ignoring climate may overestimate vaccine benefit.