Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Weekly evidence brief
Research week 2026-W45
A source-grounded weekly Research Radar brief for publications dated 2026-11-02 through 2026-11-06.
- Papers this week
- 66
- Diseases
- 34
- Countries
- 34
- Topics
- 11
Week at a glance
Treatment · Transmission dynamics · Surveillance · Vaccination · Diagnostics
This brief summarizes publication metadata and classifier links. It is not a risk assessment or a claim about changes in disease incidence.
Cited evidence
Source-level findings this week
- <b> </b> <b>O PAPEL DO FARMACÊUTICO NO ACOMPANHAMENTO DE USUÁRIOS DA PROFILAXIA PRÉ-EXPOSIÇÃO AO HIV (PrEP)</b>
Across the six included studies, adherence and continuity were associated with PrEP’s preventive effectiveness, while individual, social, and structural factors could impede access and continued engagement with health services. Individualized pharmacist guidance and integrated clinical follow-up were presented as potentially helpful, although pharmacist-exclusive interventions were not directly evaluated.
DOI 10.47820/recima21.v7i11.9551 → - A Diagnostic Algorithm Based on Urine Antigen and Blood Polymerase Chain Reaction Testing for Visceral Leishmaniasis in HIV-Coinfected Patients in Northwest Ethiopia
The supplied abstract reports blood PCR sensitivity 98% and specificity 64%, and KAtex urine antigen sensitivity 93% and specificity 81% against tissue microscopy. A sequential KAtex-first algorithm restricted PCR to 41.2% of episodes and tissue aspiration to 13.7%, with 100% sensitivity, 81% specificity, and 86% positive predictive value, meeting the WHO target product profile except for specificity.
DOI 10.4269/ajtmh.26-0104 → - A dengue sob uma perspectiva epidemiológica e sociodemográfica: uma análise sobre o estado de Minas Gerais
High incidence appeared in certain annual periods, with strong links to socioenvironmental factors, regional inequalities, and notable strain on the public health system.
DOI 10.57108/iesj.2026.6-1.1 → - A genomic toolkit for surveillance and elimination of the principal malaria vectors in Southeast Asia.
The authors released Adir1.0, a curated catalog of 540 An. dirus whole-genome sequences with cloud-based API access, and an updated Amin1.0 API. Their exploratory analysis identified population structure, candidate areas of physiological resistance, and genomic structural variation.
DOI 10.12688/wellcomeopenres.25981.2 → - A glycosylation-associated hemagglutinin substitution improves the breadth of an influenza B mRNA vaccine
The D212N substitution restored the glycosylation motif in the BV21 antigen and enhanced cross-neutralizing responses against tested heterologous strains; mice given a high dose of the modified vaccine showed 100% survival after challenge with viruses from different subclades.
DOI 10.3389/fmicb.2026.2002454 →
Monitoring context
Signals and catalogue coverage
Open catalogue evidence gaps
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Disease-level literature is available, but no recent published article has a high-confidence match to the signal geography.
Source-level findings come only from published bilingual structured summaries. Monitoring links are deterministic Research Radar relationships; they do not establish cause, validate a signal, or constitute a risk assessment.
Evidence stream
Published literature
30 of 66 publications shown
Comparative Histopathology of Yellow Fever in New and Old World Non-Human Primates: Hepatic and Extrahepatic Lesions in Susceptible Species
Pathogens
- Type
- Journal article
- Scope
- Not classified
Why it matters now According to the abstract, comparative primate pathology can support early-warning surveillance of epizootics, inform human vaccination strategies, aid wildlife conservation, and strengthen One Health outbreak preparedness.
A one health indicator-based policy and implementation gap analysis of brucellosis control in Iran: A scoping review
PLOS Neglected Tropical Diseases
- Type
- Journal article
- Scope
- Iran
Why it matters now The adapted framework can help identify control gaps and monitor programs, though external validation is needed before broader use in policy.
Trends and projections of the syphilis burden in China: an analysis of GBD 2021 data and global comparison
Frontiers in Public Health
- Type
- Journal article
- Scope
- China
Why it matters now The authors identify prenatal syphilis screening and timely, evidence-based treatment as important for preventing congenital syphilis, and emphasize improved clinician recognition of late-stage syphilis complications. They also call for investigation of whether healthcare disruptions, surveillance artifacts, or reporting changes contributed to the recent mortality and DALY trends.
Measurement Error Correction and Multidimensional Aggregation in Epidemiological Surveillance Systems: Application to the Ebola Virus Disease Epidemic in the Democratic Republic of the Congo
Asian Journal of Research in Computer Science
- Type
- Journal article
- Scope
- Democratic Republic of the Congo
Why it matters now The framework provides a formal design basis for surveillance decision-support systems that explicitly incorporate data quality, with demonstrated implications for incidence and reproduction-number estimates.
A glycosylation-associated hemagglutinin substitution improves the breadth of an influenza B mRNA vaccine
Frontiers in Microbiology
- Type
- Journal article
- Scope
- Austria
Why it matters now With no confirmed circulating B/Yamagata-lineage viruses since March 2020, the authors frame B/Victoria protection as the current priority of influenza B vaccination, and the findings are presented as informing broadly protective influenza B vaccine development.
Defining epidemiologically relevant units of cholera transmission in sub-Saharan Africa
Science Advances
- Type
- Journal article
- Scope
- Not classified
Why it matters now The findings have implications for cholera control because the transmission units and clusters may support assessment of international-spread risk and characterization of lineage-attributable incidence when sequencing data are unavailable.
The state of leprosy: increasing trends of Hansen’s disease in Florida, USA, 1996–2025
PLOS Neglected Tropical Diseases
- Type
- Journal article
- Scope
- United States
Why it matters now The rising reported incidence and concentration of cases in Brevard County provide context for monitoring leprosy burden in Florida. Florida was also among the states with the highest numbers of reported cases in 2023, when 225 new cases were reported nationally.
<b> </b> <b>O PAPEL DO FARMACÊUTICO NO ACOMPANHAMENTO DE USUÁRIOS DA PROFILAXIA PRÉ-EXPOSIÇÃO AO HIV (PrEP)</b>
RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
- Type
- Journal article
- Scope
- Not classified
Why it matters now The review identifies PrEP as an important HIV-prevention strategy and highlights adherence, access, and continuity of care as relevant considerations. It also suggests that pharmacists may help address care barriers when working within a multidisciplinary team.
Continuous directed evolution using engineered human B cell lines
Nature Communications
- Type
- Journal article
- Scope
- Not classified
Why it matters now The platform may be relevant to rapid antibody and biomolecule development for influenza-related targets, although the supplied abstract does not establish clinical effectiveness, epidemiological utility, or readiness for public-health implementation.
Identification of vertebrate hosts of mosquito blood meals following the 2017–2018 yellow fever outbreak in São Paulo State
Parasites & Vectors
- Type
- Journal article
- Scope
- Brazil
Why it matters now The anthropophilic behaviour of sylvatic vectors in urban forest fragments suggests risk of mosquito-mediated yellow fever spillover into densely populated São Paulo, supporting the authors' call for sustained vaccination and entomological/virological surveillance in peri-urban settings.
Short-term adverse events following modified vaccinia Ankara–Bavarian Nordic (MVA-BN) mpox vaccine with and without concomitant vaccines, Australia, 2022 to 2023
Eurosurveillance
- Type
- Journal article
- Scope
- Australia
Why it matters now The findings may inform future immunisation policy and public-health recommendations concerning co-administration of MVA-BN with other adult vaccines, particularly in adult men. The abstract describes this relevance as preliminary and exploratory.
Influenza Infection, Newly Diagnosed Atrial Fibrillation, and One-Year Mortality in Hospitalized Adults: A Retrospective Cohort Study
Journal of Clinical Medicine
- Type
- Cohort study
- Scope
- Not classified
Why it matters now The findings suggest that, among hospitalized adults tested for respiratory viruses, influenza was not associated with a higher short-term hazard of newly diagnosed atrial fibrillation, while atrial fibrillation identified during hospitalization was associated with increased one-year mortality.
Global return-on-investment of COVID-19 vaccines in the first year of the vaccination programme: A model-based economic evaluation
PLOS Medicine
- Type
- Journal article
- Scope
- Not classified
Why it matters now The abstract describes COVID-19 vaccines as critical to reducing global health burden and concludes that rapid vaccine development and equitable global distribution should be prioritized before and during global health crises.
Papel da enfermagem na detecção precoce da sífilis no pré-natal e a inclusão do parceiro na prevenção da reinfecção materna.
Revista ft
- Type
- Journal article
- Scope
- Not classified
Why it matters now The topic is relevant to prenatal public health because syphilis during pregnancy can be transmitted vertically and may affect mothers and fetuses. The review emphasizes prevention, timely detection, treatment, follow-up, health education, and partner engagement within prenatal care.
KẾT QUẢ NỘI KIỂM BẰNG THANG ĐO SIX SIGMA TRONG KIỂM SOÁT CHẤT LƯỢNG XÉT NGHIỆM SÀNG LỌC HBV, HCV, HIV BẰNG KỸ THUẬT ĐIỆN HOÁ PHÁT QUANG TẠI VIỆN HUYẾT HỌC - TRUYỀN MÁU TRUNG ƯƠNG
Tạp chí Y học Việt Nam
- Type
- Journal article
- Scope
- Not classified
Why it matters now The study is relevant to quality assurance and efficiency of infectious-disease screening in blood banking, with potential implications for transfusion safety, unnecessary alert reduction, and laboratory resource use. The supplied evidence does not demonstrate effects on infection incidence, donor outcomes, or patient outcomes.
Spatial and seasonal patterns of tick distribution and climate-driven shifts in Jiangsu Province, an SFTS-affected region of eastern China
PLOS Neglected Tropical Diseases
- Type
- Journal article
- Scope
- China
Why it matters now The authors place the findings in the context of climate-sensitive tick surveillance, SFTS prevention, and a One Health framework.
Absence of Plasmodium falciparum Histidine-Rich Protein 2 and 3 (Pfhrp2/3) Gene Deletions in Rizal, Palawan, the Philippines
The American Journal of Tropical Medicine and Hygiene
- Type
- Journal article
- Scope
- Philippines
Why it matters now The findings are relevant to malaria elimination in the Philippines: the authors suggest that molecular monitoring of pfhrp2 deletions in routine surveillance could improve assessment of RDT performance and support elimination strategies targeting 2030.
Seroepidemiology of human leptospirosis in subtropical Bhutan, 2024
PLOS Neglected Tropical Diseases
- Type
- Cross-sectional study
- Scope
- Bhutan
Why it matters now The findings indicate substantial prior Leptospira exposure in the sampled communities and support prevention education, protective equipment during high-risk activities, expanded epidemiologic and surveillance capacity, and stronger hospital-based diagnostics.
Hepatitis C Treatment Access With Implementation of an Antenatal Linkage-to-Care Bundle
Obstetrics & Gynecology
- Type
- Journal article
- Scope
- Not classified
Why it matters now The findings support antenatal care encounters as an opportunity to identify patients with hepatitis C, initiate curative treatment, and coordinate postpartum and infant-related care within a health system.
Anti-plasmodial activity of proteasome inhibitors against various Plasmodium species: a preclinical evaluation
Antimicrobial Agents and Chemotherapy
- Type
- Journal article
- Scope
- Not classified
Why it matters now The results identify proteasome inhibitors as potential antimalarial drug candidates in the context of increasing drug resistance and support further investigation of their structure, dosing, and combination regimens. The evidence is preclinical and does not establish clinical efficacy or safety.
Uterine Cervical Tuberculosis Mimicking Malignancy: Case Series from Ethiopia
The American Journal of Tropical Medicine and Hygiene
- Type
- Journal article
- Scope
- Ethiopia
Why it matters now The findings support including cervical tuberculosis in the differential diagnosis of cervical lesions, particularly in tuberculosis-endemic settings, because its presentation may be nonspecific and mimic malignancy.
Inhibition of type II NADH dehydrogenase in Mycobacterium tuberculosis reveals collateral vulnerability in the electron transport chain
Antimicrobial Agents and Chemotherapy
- Type
- Journal article
- Scope
- Not classified
Why it matters now The findings may inform future tuberculosis drug combinations by exploiting respiratory-chain collateral vulnerability, supporting pipeline expansion beyond standalone agents.
Post-Coronavirus Disease Condition among Nonhospitalized Patients in Honduras: A Prospective Cohort Study: 2022–2023
The American Journal of Tropical Medicine and Hygiene
- Type
- Cohort study
- Scope
- Honduras
Why it matters now The findings suggest a substantial and potentially under-recognized burden of post-COVID condition among high-risk nonhospitalized patients in Honduras, highlighting the need for further research to assess whether this reflects the burden in broader regional populations.
Modeling the potential effect of cabamiquine-pyronaridine for chemoprevention against Plasmodium falciparum malaria
Antimicrobial Agents and Chemotherapy
- Type
- Mathematical modelling
- Scope
- Not classified
Why it matters now If further clinical evaluation supports the modeled performance, the single-dose regimen could address barriers associated with multi-day treatment and potentially support less frequent seasonal chemoprevention cycles while maintaining impact.
Status of Malaria Vaccine Introduction—Africa, 2019–2024
The American Journal of Tropical Medicine and Hygiene
- Type
- Journal article
- Scope
- Ghana, Kenya, Malawi
Why it matters now The abstract identifies malaria vaccine introduction as an opportunity to integrate vaccination with preventive health services intended to reduce childhood morbidity and mortality.
Association of housing quality and altitude with malaria infection among school-aged children in mainland Tanzania
BMC Public Health
- Type
- Cross-sectional study
- Scope
- Tanzania
Why it matters now The authors suggest that context-specific housing and environmental measures could complement established malaria interventions, particularly in marginalized rural communities.
Global, regional, and national burden of syphilis in children under 5 years from 1990 to 2021
Microbiology Spectrum
- Type
- Journal article
- Scope
- Not classified
Why it matters now The findings identify mother-to-child transmission and premature neonatal mortality as major contextual concerns and indicate that prenatal screening, adequate maternal treatment, and neonatal interventions may be relevant areas for reducing burden.
Open-label Phase 1 study to evaluate drug-drug interactions between ulonivirine and islatravir in adults without HIV
Antimicrobial Agents and Chemotherapy
- Type
- Journal article
- Scope
- Iceland
Why it matters now Results support continued development of a once-weekly oral combination regimen for HIV-1 treatment based on absent meaningful interactions.
A Diagnostic Algorithm Based on Urine Antigen and Blood Polymerase Chain Reaction Testing for Visceral Leishmaniasis in HIV-Coinfected Patients in Northwest Ethiopia
The American Journal of Tropical Medicine and Hygiene
- Type
- Journal article
- Scope
- Ethiopia, United Kingdom
Why it matters now The supplied abstract states the sequential algorithm supports efficient resource use and reduces the need for invasive tissue aspiration procedures in this patient group.
Retrospective evaluation of children immunized against rabies in a pediatric emergency department
Turkish Journal of Pediatric Disease
- Type
- Journal article
- Scope
- Not classified
Why it matters now The findings identify patterns of pediatric rabies-risk exposure and describe use of post-exposure preventive measures, including vaccination completion, immunoglobulin, wound care, tetanus vaccination, antibiotics, and suturing.

