Global search

Find data and evidence

Type at least 2 characters. Use arrow keys to review and Enter to open.

Geographic evidence hub

Germany research

Published infectious-disease research classified with a high-confidence geographic relationship to Germany.

Published evidence
20
Diseases
14
Countries
25
Topics
11

Evidence stream

Published literature

20

20 publications

Point prevalence assessments of five respiratory viruses in adults ≥ 50 years of age in Germany by multi-pathogen rapid antigen testing on June 1, 2024, and December 15, 2024.

Anggitakirana M, Nacov JA, Salmanton-García J +10 more

Infection

Type
Journal article
Scope
Germany

Why it matters nowThe authors propose that community-based screening can help identify asymptomatic viral reservoirs and underreported viral circulation, such as adenovirus, linking viral detection to clinical and economic impact.

Effectiveness of seasonal mRNA COVID-19 vaccination against post COVID-19 condition between July 2023 and September 2024 among adults aged ≥ 60 years in Germany: a population-based cohort study

Nita Perumal, Caroline Peine, Annika Steffen +2 more

BMC Infectious Diseases

Type
Cohort study
Scope
Germany

Why it matters nowThe findings address vaccine-preventable PCC burden in a high-risk age group during the first post-pandemic season and are positioned as input for vaccination policy, communication, and clinical decision-making.

Peer reviewedOpen accessInfluenzaVaccination
DOI 10.1016/j.vaccine.2025.128038 ↗

Outpatient care intensity and influenza vaccination: evidence from Germany

D. Gensorowsky, B. Surmann, A.C. Meyer +6 more

Vaccine

Type
Journal article
Scope
Germany

Why it matters nowThe authors present the findings as showing that influenza vaccination coverage remains below target in the groups examined. The study suggests that routine review of vaccination status during outpatient encounters may be an important opportunity for improving uptake in adults with chronic conditions and older adults.

Peer reviewedOpen accessTick-borne encephalitisJapanese Encephalitis
DOI 10.1371/journal.pone.0334438 ↗

Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis.

Morén J, Persson B, Sörman A +6 more

PloS one

Type
Journal article
Scope
Germany

Why it matters nowThe authors note that diagnostic evaluation might be warranted for individuals experiencing delayed neurological decline, though the low prevalence limits broad applicability.

Safety and effectiveness of MVA-BN vaccination against mpox in at-risk individuals in Germany (SEMVAc and TEMVAc): a combined prospective and retrospective cohort study

David Hillus, Ngoc Han Le, Pinkus Tober-Lau +110 more

The Lancet Infectious Diseases

Type
Cohort study
Scope
Germany

Why it matters nowThe article provides Germany-specific observational evidence on MVA-BN safety and estimated effectiveness in the population studied during the 2022-2023 mpox period. Its findings may inform editorial context about vaccination evidence, including the reported difference in estimated effectiveness by HIV status, but they do not establish causality or confirm a current surveillance pattern.

Using the WHO-INTEGRATE framework to develop a COVID-19 guideline for schools, Germany

Eva Rehfuess, Lisa Pfadenhauer, Monika Nothacker +1 more

Bulletin of the World Health Organization

Type
Guideline
Scope
Germany

Why it matters nowThe guideline addressed a critical gap in reliable, globally applicable recommendations for safe and continuous school operations during the COVID-19 pandemic. The WHO-INTEGRATE framework supported transparent, structured decision-making with a whole-of-society perspective on measures to reduce SARS-CoV-2 transmission in schools.

Peer reviewedOpen accessInfluenzaGastroenteritisSurveillanceDiagnosticsOne Health
DOI 10.1080/22221751.2023.2239938 ↗

Emergence of swine influenza A virus, porcine respirovirus 1 and swine orthopneumovirus in porcine respiratory disease in Germany

Annika Graaf-Rau, Christin Hennig, Kathrin Lillie-Jaschniski +8 more

Emerging Microbes & Infections

Type
Journal article
Scope
Germany

Why it matters nowThe findings highlight the ongoing zoonotic potential of swine influenza A viruses, as demonstrated by the 2009 human pandemic, and emphasize the importance of pathogen monitoring in pig populations. The emergence of PRV1 and SOV as potential contributors to porcine respiratory disease syndrome may complicate disease control efforts.

VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment

Jon Salmanton-García, Fiona A. Stewart, Sarah Heringer +48 more

Vaccine

Type
Journal article
Scope
Austria, Belgium, Cyprus

Why it matters nowThe registry addresses a recognized barrier in pandemic response by providing a centralized infrastructure to accelerate clinical trial recruitment across European countries, potentially shortening the timeline for vaccine and treatment development during infectious disease outbreaks.

Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children

Felix Dewald, Isabelle Suárez, Ronja Johnen +54 more

Nature Communications

Type
Journal article
Scope
Germany

Why it matters nowThe method addresses practical barriers to pediatric SARS-CoV-2 surveillance by combining non-invasive sample collection with high-throughput capacity. The approach demonstrated feasibility for large-scale infection control in educational settings.

Results of the enhanced COVID-19 surveillance during UEFA EURO 2020 in Germany

Helena Heese, Adine Marquis, Michaela Diercke +6 more

Epidemiology and Infection

Type
Journal article
Scope
Germany

Why it matters nowThe findings suggest that mass gathering events can be conducted with limited COVID-19 transmission when health measures for attendees and restrictions on large public viewing are in place. The results underscore the importance of surveillance and public health regulations during mass gatherings.

Mental health concerns during the COVID-19 pandemic as revealed by helpline calls

Marius Brülhart, Valentin Klotzbücher, Rafael Lalive +1 more

Nature

Type
Journal article
Scope
Germany, France, United States

Why it matters nowThe study demonstrates that helpline data can provide real-time monitoring of mental health concerns during public health crises, complementing established surveillance approaches. The findings suggest that financial relief measures may mitigate psychological distress associated with lockdown policies.

Peer reviewedOpen accessCOVID-19SARSTreatmentVaccination
DOI 10.1038/s41586-020-2814-7 ↗

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

Ugur Sahin, Alexander Muik, Evelyna Derhovanessian +39 more

Nature

Type
Journal article
Scope
Germany

Why it matters nowEarly immunogenicity metrics indicate that the formulation triggers complementary defense pathways, positioning it as a candidate tool for future pandemic mitigation strategies pending larger efficacy evaluations.

Factors and considerations for establishing and improving seasonal influenza vaccination of health workers: Report from a WHO meeting, January 16–17, Berlin, Germany

Thomas Cherian, Kathleen F. Morales, Carsten Mantel +14 more

Vaccine

Type
Journal article
Scope
Germany

Why it matters nowHealth worker vaccination addresses dual risks of occupational infection and transmission to vulnerable patients, while also supporting pandemic preparedness. The guidance aims to help countries without policies establish them and to improve low coverage where policies exist.

Modelling norovirus transmission and vaccination

K.A.M. Gaythorpe, C.L. Trotter, A.J.K. Conlan

Vaccine

Type
Mathematical modelling
Scope
Germany

Why it matters nowNorovirus causes approximately one-fifth of acute gastroenteritis cases globally each year. With vaccines in clinical trials, model-based predictions can inform immunisation policy design and help optimize allocation across age groups depending on whether infection prevention or severe outcome prevention is prioritized.

Dot map cartograms for detection of infectious disease outbreaks: an application to Q fever, the Netherlands and pertussis, Germany

Loes Soetens, Susan Hahné, Jacco Wallinga

Eurosurveillance

Type
Journal article
Scope
Germany, Netherlands

Why it matters nowDot map cartograms may support outbreak detection and visualization by public health professionals, facilitating informed decisions for investigation and control activities.

Louse-borne relapsing fever (Borrelia recurrentis) diagnosed in 15 refugees from northeast Africa: epidemiology and preventive control measures, Bavaria, Germany, July to October 2015

Martin Hoch, Andreas Wieser, Thomas Löscher +13 more

Eurosurveillance

Type
Journal article
Scope
Germany, Somalia, Eritrea

Why it matters nowThe report highlights the need for clinicians caring for refugees traversing north Africa to recognise louse-borne relapsing fever, in order to provide timely treatment and apply preventive measures.

Peer reviewedOpen accessDengue
DOI 10.2807/ese.16.09.19805-en ↗

Autochthonous dengue fever in Croatia, August–September 2010

I Gjenero-Margan, B Aleraj, D Krajcar +18 more

Eurosurveillance

Type
Journal article
Scope
Croatia, Germany

Why it matters nowThe report documents the first apparent autochthonous dengue transmission in Croatia, demonstrating the value of cross-border case notification and the role of heightened clinical awareness combined with vector control in detecting and containing local arboviral transmission.

Food-borne norovirus-outbreak at a military base, Germany, 2009

Maria Wadl, Kathrin Scherer, Stine Nielsen +12 more

BMC Infectious Diseases

Type
Cohort study
Scope
Germany

Why it matters nowThe investigation demonstrated food-borne norovirus transmission through contaminated salad at a communal dining facility. Control measures included cohort isolation, exclusion of norovirus-positive food handlers, and kitchen disinfection, emphasizing the importance of strict hygiene and proper environmental disinfection.

furter efforts needed to achieve measles elimination in Germany: results of an outbreak investigation

Ole Wichmann

Bulletin of the World Health Organization

Type
Outbreak investigation
Scope
Germany

Why it matters nowThe findings demonstrate ongoing challenges to measles elimination in Germany, highlighting significant immunity gaps in older pediatric age groups that may undermine control strategies.

Peer reviewedOpen accessTuberculosisDiagnosticsVaccinationTreatment
DOI 10.1086/519266 ↗

Interferon- Release Assays Improve the Diagnosis of Tuberculosis and Nontuberculous Mycobacterial Disease in Children in a Country with a Low Incidence of Tuberculosis

A. K. Detjen, T. Keil, S. Roll +4 more

Clinical Infectious Diseases

Type
Journal article
Scope
Germany

Why it matters nowThe findings suggest IGRAs can reduce overdiagnosis and unnecessary treatment of tuberculosis in children by improving specificity, particularly in settings with nontuberculous mycobacterial disease and bacille Calmette-Guerin vaccination.