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India research

Published infectious-disease research classified with a high-confidence geographic relationship to India.

Published evidence
29
Diseases
25
Countries
34
Topics
14

Evidence stream

Published literature

29

29 publications

Multistakeholder Consultations on Programmatic Progress, Challenges, and Policy Priorities for Lymphatic Filariasis Elimination in India

Muhammed Jabir, Raja Jeyapal Dinesh, Adinarayanan Srividya +4 more

The American Journal of Tropical Medicine and Hygiene

Type
Journal article
Scope
India, Moldova

Why it matters nowThe synthesized recommendations supply practical frameworks for adjusting national control campaigns, optimizing funding deployment, and mitigating structural impediments that delay disease clearance objectives.

Diagnostic yield of thoracoscopic pleural biopsy in undiagnosed exudative pleural effusion and comparative analysis of pleural fluid adenosine deaminase levels.

Sharma D, Kumar S, Prakash V +6 more

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

Type
Journal article
Scope
India

Why it matters nowThe findings underscore a viable procedural pathway for resolving diagnostically ambiguous pleural conditions in regions where infectious and neoplastic respiratory diseases carry substantial prevalence.

Melioidosis in South Asia: Scientific Advances, Regional Challenges and One Health Perspectives—An Integrated Research Synthesis from the 4th South Asian Melioidosis Congress

Chiranjay Mukhopadhyay, Chimanjita Phukan, Saurav Jyoti Patgiri +3 more

Wellcome Open Research

Type
Journal article
Scope
Australia, India

Why it matters nowThe compilation frames melioidosis as an escalating yet frequently ignored infectious threat that demands improved monitoring frameworks, uniform testing standards, and interdisciplinary coordination to decrease adverse health outcomes.

Peer reviewedOpen accessSARSCOVID-19Vaccination
DOI 10.3389/fimmu.2026.1846973 ↗

The emergence of putative epistatic mutations and iSNVs in SARS-CoV-2 XBB.1.16 variants linked with alteration in immunogenic determinants

Mukesh Kumar Jogi, Sristy Shikha, Pushpendra Singh +15 more

Frontiers in Immunology

Type
Journal article
Scope
India

Why it matters nowThe work addresses how putative epistatic spike mutations in XBB.1.16 may contribute to immune evasion and variant dominance, relevant to understanding SARS-CoV-2 evolutionary trajectories.

Hidden burden of malaria in pregnancy in hard-to-reach areas of Odisha, India: challenges to elimination and the case for integrating molecular surveillance

Sonali Sandeepta, Ramakanta Rana, Jyoti Ghosal +8 more

Frontiers in Public Health

Type
Cross-sectional study
Scope
India

Why it matters nowUndetected parasitic carriage among expectant mothers complicates regional disease eradication initiatives. Integrating advanced diagnostic capabilities into routine antenatal monitoring could improve intervention targeting and support national health objectives.

Peer reviewedOpen accessRheumatic feverSurveillanceDiagnostics
DOI 10.4103/ijoc.ijoc_14_26 ↗

Rheumatic fever/rheumatic heart disease, contemporary concepts, emerging paradigms and Indian perspective

Anil Grover, K. Sudhakar Rao

Indian Journal of Cardiology

Type
Commentary
Scope
India

Why it matters nowStrengthening regional health infrastructure through coordinated diagnostic expansion and reliable medication supply chains is highlighted as essential for reducing ongoing morbidity.

Unravelling the genomic epidemiology and antigenic evolution of Chandipura virus: A genetically constrained neurotropic threat

Pooja Rani Kuri, Amit Sharma

PLOS Neglected Tropical Diseases

Type
Genomic study
Scope
India, Kenya, Nigeria

Why it matters nowAntigenic variations identified in key viral proteins indicate possible challenges for existing diagnostic assays and immunization platforms, reinforcing the value of continuous genomic tracking for health planning.

A multicenter prospective observational multi-omics study protocol to identify biomarkers for severe dengue: COMBAT study clinical protocol

Piya Paul Mudgal, Silvia Patricia Zuniga Veliz, Magda Lourda +55 more

BMC Infectious Diseases

Type
Journal article
Scope
Guatemala, India

Why it matters nowIf biomarkers are successfully identified, findings may inform improved patient triage, early intervention strategies, and novel therapeutic targets for dengue management in endemic regions.

Peer reviewedOpen accessTuberculosisTreatmentDiagnostics
DOI 10.1186/s12879-026-13544-8 ↗

Comparison of the treatment outcomes and identification of the risk factors associated with unfavorable outcomes among extra pulmonary and pulmonary tuberculosis patients under NTEP

Aditi Gupta, Abhishek Gupta, Anuradha Nadda +1 more

BMC Infectious Diseases

Type
Journal article
Scope
India

Why it matters nowDocumenting these outcome variations assists program administrators in refining case management strategies and prioritizing access to rapid microbiological verification and resistance screening tools.

Outbreak investigation of reemerging chikungunya virus in Malaysia in 2019–2020

Yik-Zheng Lim, Boon-Teong Teoh, Chee-Sieng Khor +13 more

BMC Infectious Diseases

Type
Genomic study
Scope
Malaysia, Bangladesh, China

Why it matters nowTracking these adapted viral lineages helps clarify regional transmission pathways and highlights potential shifts in pathogen behavior affecting community health planning.

Resurgent threat in a changing climate: A 20-year bibliometric analysis of global Chikungunya research evolution and pandemic preparedness

Xiaoyi Xu, Liming Ye, Yawei Liu +2 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Brazil, France, India

Why it matters nowHighlights increasing academic investment in vaccine platforms and climate-linked transmission models. Identifies structural imbalances in multinational research partnerships and recommends aligning pathogen readiness initiatives with broader environmental health planning.

Peer reviewedOpen accessLeishmaniasisKala-azarTreatmentClimate and environment
DOI 10.1371/journal.pntd.0013952 ↗

Risk factors for post-kala-azar dermal leishmaniasis (PKDL): Challenges in understanding pathophysiology

Eduard E. Zijlstra

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Bangladesh, India, Sudan

Why it matters nowThe authors emphasize the need to integrate PKDL management within broader skin disease programs and to optimize VL treatment (e.g., multidrug regimens, immune modifiers) to potentially reduce PKDL incidence.

Peer reviewedOpen accessLeprosyTreatment
DOI 10.1371/journal.pntd.0013503 ↗

Addressing multimorbidity in Leprosy: A retrospective chart review from India

Joydeepa Darlong, Karthikeyan Govindasamy, Paramjit Gill

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
India

Why it matters nowResults highlight the necessity for coordinated screening initiatives and adaptable care frameworks to manage overlapping health burdens within this marginalized demographic.

Avian influenza overview June-September 2025.

Alexakis L, Buczkowski H, Ducatez M +11 more

EFSA journal. European Food Safety Authority

Type
Journal article
Scope
Bangladesh, China, India

Why it matters nowThe data indicate that routine community exposure poses minimal threat, though individuals with professional or environmental contact with infected fauna face a marginally higher probability of contracting the virus.

Impact of the indigenous rotavirus vaccine Rotavac in the Universal Immunization Program in India during 2016–2020

Nayana P. Nair, Samarasimha N. Reddy, Sidhartha Giri +90 more

Nature Medicine

Type
Case-control study
Scope
India

Why it matters nowFindings from the abstract suggest Rotavac provided substantial protection against severe rotavirus disease under programmatic conditions in India, including against non-vaccine strains, and was characterized as performing comparably to internationally licensed vaccines in similar settings.

Spatiotemporal epidemiology and clinical manifestations of two decades of scrub typhus in India: a systematic review and meta-analysis

Rini Chaturvedi, Syed Shah Areeb Hussain, Hayavadhan Sampath +3 more

BMJ Global Health

Type
Systematic review
Scope
India

Why it matters nowThe abstract frames scrub typhus as an increasing public health concern in India and indicates that its geographic and temporal patterns may inform management and control policy. It also notes that addressing the reported upsurge may require an interdisciplinary public health approach.

Peer reviewedOpen accessInfluenzaH5N1Transmission dynamics
DOI 10.2903/j.efsa.2025.9520 ↗

Avian influenza overview March-June 2025.

Alexakis L, Buczkowski H, Ducatez M +11 more

EFSA journal. European Food Safety Authority

Type
Journal article
Scope
Bangladesh, China, United Kingdom

Why it matters nowHuman infections with currently circulating avian A(H5) clade 2.3.4.4b viruses remain rare despite widespread animal circulation; the assessed EU/EEA risk is low for the general public and low-to-moderate for those with occupational exposure to infected animals or contaminated environments.

SARS-CoV-2 Alchemy: Understanding the dynamics of age, vaccination, and geography in the evolution of SARS-CoV-2 in India

Mansi Patel, Uzma Shamim, Umang Umang +2 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
India

Why it matters nowThe paper presents characterization of viral substitution patterns across demographic, geographic, and vaccination-period categories as relevant to ongoing monitoring of SARS-CoV-2 evolution and pandemic preparedness. These implications are based on the study's reported genomic patterns and do not establish causal effects or confirm a current surveillance signal.

Seasonal influenza surveillance and vaccination policies in the WHO South-East Asian Region

Saleh Haider, Md Zakiul Hassan

BMJ Global Health

Type
Journal article
Scope
Bangladesh, Bhutan, Indonesia

Why it matters nowThe region's high population density and role as a potential epicenter for future influenza pandemics makes comprehensive vaccination and surveillance policies critical for pandemic preparedness. Low vaccine uptake and limited surveillance data hinder effective public health responses across most SEAR countries.

Updating estimates of Plasmodium knowlesi malaria risk in response to changing land use patterns across Southeast Asia

Ruarai J. Tobin, Lucinda E. Harrison, Meg K. Tully +8 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Indonesia, India, Malaysia

Why it matters nowThe findings may help inform geographic prioritization for P. knowlesi diagnosis, treatment planning, surveillance and sampling, as described by the authors. The abstract also places the work in the context of malaria elimination planning.

A Brighton Collaboration standardized template with key considerations for a benefit/risk assessment for an inactivated viral vaccine against Chikungunya virus

Libia Milena Hernandez, K. Sumathy, Sushant Sahastrabuddhe +5 more

Vaccine

Type
Journal article
Scope
India

Why it matters nowInactivated viral vaccine technology has been applied to diseases of global health threat, and this chikungunya vaccine candidate offers an effective, flexible system for high-yield manufacturing with favorable stability for distribution.

The current burden of Japanese encephalitis and the estimated impacts of vaccination: Combining estimates of the spatial distribution and transmission intensity of a zoonotic pathogen

Sean M. Moore

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Bangladesh, China, India

Why it matters nowThe estimates identify countries and populations where the authors project that increased vaccination coverage could have a substantial effect on Japanese encephalitis burden. The abstract also indicates that reported cases and deaths are substantially below the estimated burden in many endemic countries.

Disease surveillance during a large religious mass gathering in India: The Prayagraj Kumbh 2019 experience

Vikasendu Aggrawal, Tanzin Dikid, S.K. Jain +28 more

International Journal of Infectious Diseases

Type
Journal article
Scope
India

Why it matters nowThe article indicates that incorporating onsite surveillance into mass-gathering planning can support detection, verification, and response to reported disease signals. It identifies acute respiratory illness as a leading reported morbidity category and recommends strengthening its diagnosis and management capacity for future mass gatherings.

Costs incurred by patients with drug-susceptible pulmonary tuberculosis in semi-urban and rural settings of Western India

Mihir P. Rupani, Adithya Cattamanchi, Priya B. Shete +3 more

Infectious Diseases of Poverty

Type
Cross-sectional study
Scope
India, United States

Why it matters nowWhile treatment completion rates were high and patient costs were relatively low, negative financial consequences—including catastrophic costs, borrowing, and job loss—persisted even in this low-cost setting, indicating potential benefit from universal cash transfer programs.

Intensely clustered outbreak of visceral leishmaniasis (kala-azar) in a setting of seasonal migration in a village of Bihar, India

Arvind Kumar, Suman Saurabh, Sarosh Jamil +1 more

BMC Infectious Diseases

Type
Outbreak investigation
Scope
India

Why it matters nowThe outbreak demonstrates vulnerability in low-endemic areas and highlights gaps in case-finding, treatment delays, incomplete vector control coverage, and the role of social and economic determinants in kala-azar transmission. The findings underscore the need for a routine outbreak response framework within the elimination programme.

The Burden of Typhoid and Paratyphoid in India: Systematic Review and Meta-analysis

Jacob John, Carola J. C. Van Aart, Nicholas C. Grassly

PLOS Neglected Tropical Diseases

Type
Systematic review
Scope
India

Why it matters nowThe findings indicate that typhoid remains a significant public health challenge in India despite apparent declines in prevalence, particularly among young children, and suggest that newly-licensed conjugate vaccines for infant immunization could address this burden, especially amid growing antimicrobial resistance.

Coverage and Effectiveness of Kyasanur Forest Disease (KFD) Vaccine in Karnataka, South India, 2005–10

Gudadappa S. Kasabi, Manoj V. Murhekar, Vijay K. Sandhya +4 more

PLoS Neglected Tropical Diseases

Type
Journal article
Scope
India

Why it matters nowThe findings indicate suboptimal vaccination uptake and reduced vaccine effectiveness in the field setting, underscoring the need to expand coverage and investigate reasons for the diminished protection reported here.

Peer reviewedOpen accessGastroenteritisTreatmentVaccinationSurveillance
DOI 10.1093/cid/cis761 ↗

The Global Enteric Multicenter Study (GEMS): Impetus, Rationale, and Genesis

M. M. Levine, K. L. Kotloff, J. P. Nataro +1 more

Clinical Infectious Diseases

Type
Case-control study
Scope
Bangladesh, Gambia, India

Why it matters nowThe work addresses diarrheal disease, cited as one of the top two causes of young child mortality in the developing world, and aims to inform prioritization of water/sanitation, hygiene, and vaccine strategies.

Inapparent infections and cholera dynamics

Aaron A. King, Edward L. Ionides, Mercedes Pascual +1 more

Nature

Type
Journal article
Scope
India

Why it matters nowThe findings suggest that inapparent infections are central to interpreting cholera outbreak patterns and that environmental sources may be critical to sustaining endemicity, with implications for transmission theory and control strategies.